Reactome | thoc5 [nucleoplasm]

thoc5 [nucleoplasm]

Stable Identifier

R-DME-8849111

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

THOC5, Q9W1F4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - RNA Polymerase II Transcription Termination (Drosophila melanogaster)
    - Cleavage of mRNA at the 3'-end (Drosophila melanogaster)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)

Metabolism of RNA (Drosophila melanogaster)

- Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
  - Transport of Mature Transcript to Cytoplasm (Drosophila melanogaster)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Drosophila melanogaster)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Drosophila melanogaster)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Drosophila melanogaster)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Drosophila melanogaster)
        
        TREX (minus DDX39B) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
  - mRNA 3'-end processing (Drosophila melanogaster)
    - Cleavage of mRNA at the 3'-end (Drosophila melanogaster)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
    - mRNA polyadenylation (Drosophila melanogaster)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Drosophila melanogaster)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Drosophila melanogaster)
        
        THO complex [nucleoplasm] (Drosophila melanogaster)
        
        thoc5 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9W1F4

Gene Names

thoc5

Reference Genes

BioGPS Gene:37810 thoc5

ENSEMBL:FBgn0034939

Flybase:FBgn0034939

KEGG Gene (Drosophila melanogaster):Dmel_CG2980 thoc5

Monarch:37810 thoc5

NCBI Gene:37810 thoc5

UCSC:Q9W1F4 thoc5

Reference Transcript

RefSeq:NM_138012.3 thoc5

Other Identifiers

154045_at

1635668_at

37810

GO:0000228

GO:0000346

GO:0000347

GO:0000445

GO:0003674

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005635

GO:0005694

GO:0005730

GO:0005737

GO:0006351

GO:0006355

GO:0006406

GO:0006913

GO:0007140

GO:0016020

GO:0022414

GO:0031965

GO:0031990

GO:0032786

GO:0032991

GO:0043021

GO:0043226

GO:0140013

Participates

as a component of

THO complex [nucleoplasm] (Drosophila melanogaster)

Inferred From

THOC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_611856.1

Flybase

FBgn0034939

PRO

Q9W1F4