Reactome | Ubc10 [cytosol]

Ubc10 [cytosol]

Stable Identifier

R-DME-8864201

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Ub-C86-UBE2L3, Q7K738

Locations in the PathwayBrowser

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Autophagy (Drosophila melanogaster)

- Macroautophagy (Drosophila melanogaster)
  - Selective autophagy (Drosophila melanogaster)
    - Mitophagy (Drosophila melanogaster)
      - PINK1-PRKN Mediated Mitophagy (Drosophila melanogaster)
        
        PRKN ubiquitinates MOM substrates (Drosophila melanogaster)
        
        Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Drosophila melanogaster)
        
        Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Drosophila melanogaster)
        
        Ubc10 [cytosol] (Drosophila melanogaster)

Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Protein ubiquitination (Drosophila melanogaster)
    - Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Drosophila melanogaster)
      - UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Drosophila melanogaster)
        
        Ub:E2 (UBA1 substrate) [cytosol] (Drosophila melanogaster)
        
        Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Drosophila melanogaster)
        
        Ubc10 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7K738

Gene Names

Ubc10

Reference Genes

BioGPS Gene:37035 Ubc10

CTD Gene:37035 Ubc10

ENSEMBL:FBgn0026316

FlyBase:FBgn0026316

KEGG:dme:Dmel_CG5788 Ubc10

Monarch:37035 Ubc10

NCBI Gene:37035 Ubc10

UCSC:Q7K738 Ubc10

Reference Transcript

RefSeq:NM_058066.4 Ubc10

Other Identifiers

144122_at

1634533_at

37035

GO:0000151

GO:0000209

GO:0003824

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0006511

GO:0016567

GO:0016740

GO:0016874

GO:0031625

GO:0043226

GO:0061631

GO:0097039

GO:0140096

Participates

as a member of

as a component of

Ub:UBE2L3 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Ubc10 [nucleoplasm]

Ubc10 [cytosol]

Inferred From

Ub-C86-UBE2L3 [cytosol] (Homo sapiens)

Modified Residues

Name

S-(glycyl)-L-cysteine (Cys-Gly) at 86 (in Homo sapiens)

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

NP_477414.1

ENSEMBL

FBpp0088522, FBtr0089553

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