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What is Reactome ?
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SH3GLs [cytosol]
Stable Identifier
R-DME-8867746
Type
Set [CandidateSet]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
endophilins
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
EGFR downregulation (Drosophila melanogaster)
Assembly of EGFR complex in clathrin-coated vesicles (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
CBL-mediated ubiquitination of CIN85 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
Ub-CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGFR binds EPS15, EPN1, EPS15L1 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGFR non-clathrin mediated endocytosis (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGFR phosphorylates EPS15 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PTPN3 dephosphorylates EPS15 (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Sprouty sequesters CBL away from active EGFR (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
Epsin family proteins bind ubiquitinated cargo (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
ubiquitinated cargo [plasma membrane] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
SH3GLs [cytosol] (Drosophila melanogaster)
Participants
members
SH3GL2 dimer [cytosol]
(Drosophila melanogaster)
candidates
SH3GL1 dimer [cytosol]
(Drosophila melanogaster)
SH3GL3 dimer [cytosol]
(Drosophila melanogaster)
Participates
as a component of
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
Ub-CIN85:endophilin [cytosol] (Drosophila melanogaster)
CIN85:endophilin [cytosol] (Drosophila melanogaster)
as an input of
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
Inferred From
SH3GLs [cytosol]
(Homo sapiens)
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