Reactome | phospho-p-Y397-LYN [cytosol]

phospho-p-Y397-LYN [cytosol]

Stable Identifier

R-DME-8942608

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

P00528

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P00528

Reference Genes

BioGPS Gene:48973

CTD Gene:48973

ENSEMBL:FBgn0262733

FlyBase:FBgn0262733

KEGG:dme:Dmel_CG7524

Monarch:48973

NCBI Gene:48973

UCSC:P00528

Reference Transcript

Other Identifiers

143366_at

1634871_s_at

1641253_at

48973

GO:0002009

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005102

GO:0005515

GO:0005524

GO:0005829

GO:0005886

GO:0006468

GO:0007010

GO:0007155

GO:0007169

GO:0007293

GO:0007300

GO:0007301

GO:0007349

GO:0007411

GO:0007424

GO:0007435

GO:0007616

GO:0008064

GO:0008302

GO:0008335

GO:0016043

GO:0016319

GO:0016740

GO:0018108

GO:0022414

GO:0030036

GO:0030046

GO:0030154

GO:0030708

GO:0030717

GO:0030723

GO:0031234

GO:0034330

GO:0034332

GO:0035331

GO:0035332

GO:0036058

GO:0045087

GO:0045172

GO:0045742

GO:0045743

GO:0045874

GO:0045886

GO:0048167

GO:0048468

GO:0048477

GO:0048513

GO:0048856

GO:0050877

GO:0065008

GO:0090136

GO:0098542

GO:0120176

GO:0140096

Participates

as a candidate of

(p-Y342-PTK6,p-Y397-LYN,p-Y226,Y393-ABL1,p-Y419-SRC,p-5Y-JAK2) [cytosol] (Drosophila melanogaster)

Other forms of this molecule

SRC-2 [cytosol]

phospho-MyrG-p-Y419-SRC [plasma membrane]

FYN [cytosol]

LCK [cytosol]

SRC-1 [plasma membrane]

phospho-MyrG-p-Y426-YES1 [plasma membrane]

phospho-MyrG-p-Y420-FYN-1 [plasma membrane]

phospho-MyrG,p-Y530-SRC [plasma membrane]

phospho-p-Y420-FYN [cytosol]

LYN [cytosol]

phospho-p-Y419-SRC [cytosol]

FGR [cytosol]

YES1 [cytosol]

HCK [cytosol]

MyrG2-PalmC3-LYN [plasma membrane]

phospho-p-Y397-LYN [plasma membrane]

LYN [plasma membrane]

phospho-p-Y394-LCK [plasma membrane]

phospho-p-Y419-SRC-1 [plasma membrane]

MyrG-SRC [plasma membrane]

phospho-p-S21,Y420-FYN [cytosol]

FGR [secretory granule lumen]

FGR [extracellular region]

phospho-p-Y419-SRC [cytosol]

SRC [cytosol]

phospho-p-HCK [cytosol]

MyrG2-PalmC3-LYN [endocytic vesicle membrane]

MyrG2-PalmC3-LYN [lysosomal membrane]

Inferred From

p-Y397-LYN [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 397 (in Homo sapiens)

Coordinate

397

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001189051.1, NP_524934.2, NP_001014561.1, NP_001014562.1, NP_001014564.1, NP_001014563.1, NP_001246628.1, NP_001246629.1

ENSEMBL

FBtr0100508, FBtr0100505, FBtr0100507, FBtr0100504, FBpp0293527, FBtr0304989, FBpp0293526, FBpp0291750, FBpp0099947, FBpp0099948, FBtr0073321, FBpp0099946, FBtr0302594, FBpp0073177, FBpp0099944, FBtr0304990

PRO

P00528

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11346 Raf	20	Phospho PHL [plasma membrane] (R-DME-205859) PHL [cytosol] (R-DME-205713) phospho-p-S299,S302,T452,T455,S582 ARAF [cytosol] (R-DME-5672646) phospho-p-S446,T599,S602,S729 BRAF [cytosol] (R-DME-5672676) phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-DME-5672664) phospho-p-S446,S729-BRAF [cytosol] (R-DME-5672673) phospho-p-S446,T599,S602,S729 BRAF [plasma membrane] (R-DME-5672679) phospho-p-S299,S302,T452,T455,S582 ARAF [plasma membrane] (R-DME-5672648) phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-DME-5672665) phospho-p-S582 ARAF [cytosol] (R-DME-5672681) phospho-p-S621-RAF1 [cytosol] (R-DME-206028) RAF1 [cytosol] (R-DME-167205) BRAF [cytosol] (R-DME-167224) phospho-p-S214,S582 ARAF [cytosol] (R-DME-5672639) phospho-p-S259,S621-RAF1 [cytosol] (R-DME-109786) phospho-p-S365,S446,S729 BRAF [cytosol] (R-DME-5672667) phospho-p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-DME-5675420) phospho-p-S621-RAF1 [plasma membrane] (R-DME-206222) phospho-hyperphosphorylated RAF1 [plasma membrane] (R-DME-5675193) phospho-hyperphosphorylated BRAF [plasma membrane] (R-DME-5675199)	0.544	3
UniProt:Q03720	1	slo [plasma membrane] (R-DME-2534368)	0.544	3
UniProt:Q9VLA2 GCM2			0.488	2

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