Reactome | Pdha [mitochondrial matrix]

Pdha [mitochondrial matrix]

Stable Identifier

R-DME-8953513

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial matrix

Synonyms

PDHA2, Q7KVX1

Locations in the PathwayBrowser

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Metabolism (Drosophila melanogaster)

- Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
  - Pyruvate metabolism (Drosophila melanogaster)
    - PDH complex synthesizes acetyl-CoA from PYR (Drosophila melanogaster)
      - DLAT trimer transfers acetyl to CoA (Drosophila melanogaster)
        
        PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
      - DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)
        
        PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
      - PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
    - Regulation of pyruvate metabolism (Drosophila melanogaster)
      - Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
        
        PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
        
        PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        PDP1,2 dephosphorylate p-lipo-PDH (Drosophila melanogaster)
        
        PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)

Signal Transduction (Drosophila melanogaster)

- Signaling by Nuclear Receptors (Drosophila melanogaster)
  - Signaling by Retinoic Acid (Drosophila melanogaster)
    - PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
      - PDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
      - p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)
        
        phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
        
        PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
        
        PDHA1,2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)
        
        Pdha [mitochondrial matrix] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7KVX1

Gene Names

Pdha

Reference Genes

BioGPS Gene:31406 Pdha

ENSEMBL:FBgn0028325

Flybase:FBgn0028325

Monarch:31406 Pdha

NCBI Gene:31406 Pdha

UCSC:Q7KVX1 Pdha

Reference Transcript

RefSeq:NM_167017.3 Pdha

Other Identifiers

153790_at

1635253_a_at

31406

GO:0003824

GO:0004738

GO:0004739

GO:0005739

GO:0005967

GO:0006086

GO:0006090

GO:0006790

GO:0016491

GO:0016624

GO:0043226

GO:0043231

GO:0055086

GO:1901135

Participates

as a member of

Homologues of PDHA2 [mitochondrial matrix] (Drosophila melanogaster)

Other forms of this molecule

Pdha [mitochondrial matrix]

Inferred From

PDHA2 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_726945.1

Flybase

FBgn0028325

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