Reactome | Dmel\CG5111 [cytosol]

Dmel\CG5111 [cytosol]

Stable Identifier

R-DME-8956129

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

NUB1-1, Q9VBQ3

Locations in the PathwayBrowser for interactor UniProt:Q8T3Y0

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External Reference Information

External Reference

UniProt:Q9VBQ3

Gene Names

Dmel\CG5111

Reference Genes

BioGPS Gene:43085 Dmel\CG5111

ENSEMBL:FBgn0039343

Flybase:FBgn0039343

KEGG Gene (Drosophila melanogaster):Dmel_CG5111 Dmel\CG5111

Monarch:43085 Dmel\CG5111

NCBI Gene:43085 Dmel\CG5111

UCSC:Q9VBQ3 Dmel\CG5111

Reference Transcript

RefSeq:NM_143145.1 Dmel\CG5111

Other Identifiers

150593_at

1629489_at

43085

GO:0003674

GO:0005515

GO:0005634

GO:0005737

GO:0016567

GO:0030163

GO:0036211

GO:0043226

GO:2000058

Participates

as an output of

26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Drosophila melanogaster)

as an input of

NEDD8 and UBD bind NUB1 and the 26S proteasome (Drosophila melanogaster)

as a component of

NEDD8,UBD:NUB1:26S proteasome [cytosol] (Drosophila melanogaster)

Inferred From

NUB1 [cytosol] (Homo sapiens)

NUB1-1 [cytosol] (Homo sapiens)

NUB1-2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_651402.1

Flybase

FBgn0039343

Interactors (31)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9W450	4	Grip [cytosol] (R-DME-416633) Grip [cytosol] (R-DME-416643) Grip [plasma membrane] (R-DME-416632) Grip [plasma membrane] (R-DME-416638)	0.666	4
UniProt:Q8T3Y0	1	SIAH2 [cytosol] (R-DME-374566-2)	0.621	3
UniProt:Q8IRC7 AWH			0.488	2
UniProt:M9PCG2	6	Sox21b [nucleoplasm] (R-DME-5625834) Sox21b [nucleoplasm] (R-DME-5627706) Sox21b [nucleoplasm] (R-DME-5625835) Sox21b [nucleoplasm] (R-DME-5625832) Sox21b [nucleoplasm] (R-DME-5627712) Sox21b [nucleoplasm] (R-DME-452271)	0.488	2
UniProt:Q9VBX2 MOC2B			0.488	2
UniProt:Q8I062 Q8I062			0.488	2
UniProt:Q0IGU0 Q0IGU0			0.488	2
UniProt:E1JGZ4 E1JGZ4			0.488	2
UniProt:Q8IPA8 Q8IPA8			0.488	2
UniProt:P25158 OSKA			0.488	2
UniProt:Q9VEG8 Q9VEG8			0.488	2
UniProt:Q9VNI0 Q9VNI0			0.488	2
UniProt:A0A0B4KEQ7 A0A0B4KEQ7			0.488	2
UniProt:Q8MYR8 Q8MYR8			0.488	2
UniProt:Q9VZD7 Q9VZD7			0.488	2
UniProt:H1UUK0 H1UUK0			0.488	2
UniProt:Q9VRY7 Q9VRY7			0.488	2
UniProt:P18486-2 P184862			0.488	2
UniProt:P09087 ABDB			0.488	2
UniProt:Q9VK21 Q9VK21			0.488	2
UniProt:A1Z6E0	2	gus [cytosol] (R-DME-976048) gus [cytosol] (R-DME-976024)	0.488	2
UniProt:Q6IDH2	1	Nadk1a [cytosol] (R-DME-197282)	0.488	2
UniProt:Q4V5G4 Q4V5G4			0.488	2
UniProt:Q9VWN2 Q9VWN2			0.488	2
UniProt:A1Z866 A1Z866			0.488	2
UniProt:Q9VUX1	1	mRpS31 [mitochondrial inner membrane] (R-DME-5368198)	0.488	2
UniProt:D5SHU5 D5SHU5			0.488	2
UniProt:P08985	1	His2Av [nucleoplasm] (R-DME-8862427)	0.488	2
UniProt:Q9W3T2 Q9W3T2			0.488	2
UniProt:Q9VEF0	7	ZNF383 [nucleoplasm] (R-DME-1247521-2) ZNF707 [nucleoplasm] (R-DME-2454161-2) ZNF692 [nucleoplasm] (R-DME-2454144-2) ZNF671 [nucleoplasm] (R-DME-2248876-2) ZNF660 [nucleoplasm] (R-DME-2248875-2) ZNF667 [nucleoplasm] (R-DME-2248870-2) ZNF662 [nucleoplasm] (R-DME-2248867-2)	0.488	2
UniProt:P21461	2	SIAH2 [cytosol] (R-DME-374566) SIAH1 [cytosol] (R-DME-374563)	0.488	2

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