Reactome | Spn43Ad [endoplasmic reticulum lumen]

Spn43Ad [endoplasmic reticulum lumen]

Stable Identifier

R-DME-8956709-14

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum lumen

Synonyms

SERPINA1, Q8SYY7

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Post-translational protein phosphorylation (Drosophila melanogaster)
    - FAM20C phosphorylates FAM20C substrates (Drosophila melanogaster)
      - FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Drosophila melanogaster)
        
        FAM20C substrates [endoplasmic reticulum lumen] (Drosophila melanogaster)
        
        Homologues of SERPINA1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
        
        Spn43Ad [endoplasmic reticulum lumen] (Drosophila melanogaster)
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Drosophila melanogaster)
  - FAM20C phosphorylates FAM20C substrates (Drosophila melanogaster)
    - FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Drosophila melanogaster)
      - FAM20C substrates [endoplasmic reticulum lumen] (Drosophila melanogaster)
        
        Homologues of SERPINA1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
        
        Spn43Ad [endoplasmic reticulum lumen] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q8SYY7

Gene Names

Spn43Ad

Reference Genes

BioGPS Gene:35639 Spn43Ad

CTD Gene:35639 Spn43Ad

ENSEMBL:FBgn0044011

FlyBase:FBgn0044011

KEGG:dme:Dmel_CG1859 Spn43Ad

Monarch:35639 Spn43Ad

NCBI Gene:35639 Spn43Ad

UCSC:Q8SYY7 Spn43Ad

Reference Transcript

RefSeq:NM_136417.3 Spn43Ad

Other Identifiers

146725_at

1628564_at

35639

GO:0004867

GO:0005615

GO:0010466

GO:0098772

Participates

as a member of

Homologues of SERPINA1 [endoplasmic reticulum lumen] (Drosophila melanogaster)

Other forms of this molecule

Spn43Ad [extracellular region]

Spn43Ad [endoplasmic reticulum lumen]

phospho-Spn43Ad [endoplasmic reticulum lumen]

Spn43Ad [extracellular region]

Spn43Ad [ficolin-1-rich granule membrane]

Spn43Ad [plasma membrane]

Spn43Ad [secretory granule lumen]

Spn43Ad [extracellular region]

Spn43Ad [azurophil granule lumen]

Spn43Ad [extracellular region]

Spn43Ad [ficolin-1-rich granule lumen]

Spn43Ad [extracellular region]

Spn43Ad [endoplasmic reticulum lumen]

Spn43Ad [COPII-coated ER to Golgi transport vesicle]

Spn43Ad [endoplasmic reticulum-Golgi intermediate compartment membrane]

Spn43Ad [lysosomal lumen]

Spn43Ad [endoplasmic reticulum lumen]

Spn43Ad [extracellular region]

Spn43Ad [plasma membrane]

Spn43Ad [extracellular region]

Spn43Ad [platelet dense granule lumen]

Spn43Ad [extracellular region]

Spn43Ad [platelet alpha granule lumen]

Spn43Ad [extracellular region]

Inferred From

SERPINA1 [endoplasmic reticulum lumen] (Homo sapiens)

Cross References

RefSeq

NP_610261.1

ENSEMBL

FBpp0088124, FBtr0089053

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7KTX7	4	PRKN [cytosol] (R-DME-201579) phospho-p-S65-PRKN [cytosol] (R-DME-9834954) phospho-p-S9-PRKN [cytosol] (R-DME-9793481) polyUb-PARK2 [cytosol] (R-DME-5689094)	0.488	2

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