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phospho-p-T185-MAPK1 [cytosol]
Stable Identifier
R-DME-9635773
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P40417
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PTPN7 dephosphorylates p-T,Y-MAPKs (Drosophila melanogaster)
PTPN7:p-T-MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185-MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185-MAPK1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P40417
Reference Genes
BioGPS Gene:3354888
CTD Gene:3354888
ENSEMBL:FBgn0003256
Flybase:FBgn0003256
KEGG Gene (Drosophila melanogaster):Dmel_CG12559
Monarch:3354888
NCBI Gene:3354888
Reference Transcript
RefSeq:NM_001015123.3
RefSeq:NM_001015121.3
RefSeq:NM_001300706.2
RefSeq:NM_001110879.2
RefSeq:NM_001015122.3
RefSeq:NM_001110878.4
Other Identifiers
1629549_s_at
3354888
GO:0000165
GO:0000166
GO:0000278
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006468
GO:0006914
GO:0007049
GO:0007166
GO:0007173
GO:0007362
GO:0007430
GO:0007465
GO:0007474
GO:0007476
GO:0007479
GO:0007552
GO:0008134
GO:0008284
GO:0008286
GO:0008293
GO:0008340
GO:0008543
GO:0009267
GO:0009605
GO:0010468
GO:0016242
GO:0016301
GO:0016310
GO:0016740
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0031594
GO:0033554
GO:0034614
GO:0035169
GO:0035170
GO:0035202
GO:0035556
GO:0036211
GO:0042060
GO:0043226
GO:0045500
GO:0045793
GO:0046534
GO:0046843
GO:0048010
GO:0048149
GO:0048856
GO:0050804
GO:0051091
GO:0051607
GO:0060446
GO:0070371
GO:0071243
GO:0071276
GO:0090303
GO:0098542
GO:0106310
GO:0140096
GO:0140297
GO:2000826
GO:2001023
Participates
as a component of
p-T185-MAPK1 dimer [cytosol] (Drosophila melanogaster)
Other forms of this molecule
MAPK1 [azurophil granule lumen]
MAPK1 [extracellular region]
MAPK1 [ficolin-1-rich granule lumen]
MAPK1 [nucleoplasm]
MAPK1 [cytosol]
phospho-p-T185,Y187-MAPK1 [cytosol]
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
Inferred From
p-T185-MAPK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001287635.1
,
NP_001015122.1
,
NP_001015123.1
,
NP_001104349.1
,
NP_001015121.3
,
NP_001104348.2
Flybase
FBgn0003256
IntEnz
2.7.11.24
PRO
P40417
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9U1H0 CIC
0.593
3
UniProt:Q24106 HID
0.59
3
UniProt:Q9V393 krz
8
krz [cytoplasmic vesicle membrane]
(R-DME-351187-3)
krz [Golgi membrane]
(R-DME-350831-3)
krz [lysosomal membrane]
(R-DME-432701-3)
krz [cytosol]
(R-DME-6783000)
krz [cytosol]
(R-DME-6783186-3)
Krz [cytosol]
(R-DME-2071841)
krz [cytosol]
(R-DME-416464)
krz [cytosol]
(R-DME-264470-3)
0.544
12
UniProt:Q24324 Dsor1
9
DSOR1 [cytosol]
(R-DME-205968)
phospho-p-S,218, S222,T292 MAP2K1 [cytosol]
(R-DME-5674490)
phospho-p-S,T-MAP2K2 [cytosol]
(R-DME-109848)
phospho-p-T286,T292-MAP2K1 [cytosol]
(R-DME-112374)
phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]
(R-DME-112339)
MAP2K1 [cytosol]
(R-DME-59502)
MAP2K2 [cytosol]
(R-DME-59504)
phospho-p-S222,S226-MAP2K2 [cytosol]
(R-DME-169292)
phospho-p-S218,S222-MAP2K1 [cytosol]
(R-DME-109837)
0.534
2
UniProt:Q24496 Q24496
0.524
2
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
UniProt:Q9W2K3 Q9W2K3
0.488
2
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