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ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]
Stable Identifier
R-DME-9665220
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
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Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
Drug-mediated inhibition of ERBB2 signaling (Drosophila melanogaster)
ERBB2 binds TKIs (Drosophila melanogaster)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Drosophila melanogaster)
Trans-autophosphorylation of ERBB2 heterodimers (Drosophila melanogaster)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CDC37 [cytosol]
(Drosophila melanogaster)
ERBB2:TKIs [plasma membrane]
(Drosophila melanogaster)
Ghost homologue of ERBIN [plasma membrane]
(Drosophila melanogaster)
HSP90 [cytosol]
(Drosophila melanogaster)
Participates
as an output of
ERBB2 binds TKIs (Drosophila melanogaster)
This entity regulates
Negatively
Trans-autophosphorylation of ERBB2 heterodimers
(Drosophila melanogaster)
Inferred From
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]
(Homo sapiens)
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