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SPAST [cytosol]
Stable Identifier
R-DME-9668426
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q8I0P1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Nuclear Envelope (NE) Reassembly (Drosophila melanogaster)
Sealing of the nuclear envelope (NE) by ESCRT-III (Drosophila melanogaster)
SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Drosophila melanogaster)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Drosophila melanogaster)
SPAST [cytosol] (Drosophila melanogaster)
SPAST [cytosol] (Drosophila melanogaster)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Drosophila melanogaster)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Drosophila melanogaster)
SPAST [cytosol] (Drosophila melanogaster)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Drosophila melanogaster)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Drosophila melanogaster)
SPAST [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8I0P1
Reference Genes
BioGPS Gene:42846
ENSEMBL:FBgn0039141
Flybase:FBgn0039141
KEGG Gene (Drosophila melanogaster):Dmel_CG5977
Monarch:42846
NCBI Gene:42846
UCSC:Q8I0P1
Reference Transcript
RefSeq:NM_170115.3
RefSeq:NM_001316509.1
RefSeq:NM_142949.4
Other Identifiers
154205_at
1628019_a_at
1629123_at
42846
GO:0000022
GO:0000070
GO:0000166
GO:0000226
GO:0000278
GO:0003824
GO:0005515
GO:0005524
GO:0005694
GO:0005737
GO:0005811
GO:0005813
GO:0005815
GO:0005819
GO:0005856
GO:0005874
GO:0006629
GO:0007010
GO:0007018
GO:0007026
GO:0007049
GO:0007059
GO:0007079
GO:0007399
GO:0007626
GO:0008017
GO:0008021
GO:0008092
GO:0008344
GO:0008568
GO:0015630
GO:0016020
GO:0016787
GO:0016853
GO:0016887
GO:0023052
GO:0030154
GO:0031117
GO:0031410
GO:0031594
GO:0034214
GO:0034330
GO:0035099
GO:0043014
GO:0043195
GO:0043226
GO:0045834
GO:0045886
GO:0045887
GO:0048691
GO:0048856
GO:0048870
GO:0050775
GO:0050803
GO:0051013
GO:0051301
GO:0065003
GO:0140014
GO:0140096
GO:0140657
GO:1900074
GO:1900075
GO:2000331
Participates
as an input of
SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Drosophila melanogaster)
as a component of
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Drosophila melanogaster)
Inferred From
SPAST [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_651206.3
,
NP_732941.2
,
NP_001303438.1
Flybase
FBgn0039141
PRO
Q8I0P1
PDB
6NYW
,
6P13
,
6P10
,
6P12
,
6P14
,
6P11
,
3B9P
,
6NYV
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IR14 Q8IR14
0.488
2
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