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Go!
OPTN [cytosol]
Stable Identifier
R-DME-9687907
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9GYV5
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Selective autophagy (Drosophila melanogaster)
Mitophagy (Drosophila melanogaster)
PINK1-PRKN Mediated Mitophagy (Drosophila melanogaster)
OPTN, TBK1 bind ubiquitinated MOM proteins (Drosophila melanogaster)
OPTN [cytosol] (Drosophila melanogaster)
TBK1:OPTN:K63-polyUb-mitochondrial proteins [cytosol] (Drosophila melanogaster)
OPTN [cytosol] (Drosophila melanogaster)
TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Drosophila melanogaster)
TBK1:OPTN:K63-polyUb-mitochondrial proteins [cytosol] (Drosophila melanogaster)
OPTN [cytosol] (Drosophila melanogaster)
p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] (Drosophila melanogaster)
OPTN [cytosol] (Drosophila melanogaster)
p-S-TBK1 phosphorylates OPTN (Drosophila melanogaster)
p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] (Drosophila melanogaster)
OPTN [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9GYV5 key
Gene Names
key, IKKGAMMA, CG16910
Chain
chain:1-387
Reference Genes
BioGPS Gene:37967 key
KEGG Gene (Drosophila melanogaster):Dmel_CG16910 key
Monarch:37967 key
NCBI Gene:37967 key
UCSC:Q9GYV5 key
Reference Transcript
RefSeq:NM_079132.4 key
Other Identifiers
153921_at
1623762_at
37967
GO:0002230
GO:0002376
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006955
GO:0006963
GO:0023052
GO:0030163
GO:0043122
GO:0043226
GO:0045087
GO:0045089
GO:0045944
GO:0046872
GO:0050829
GO:0051607
GO:0061057
GO:0070530
GO:0098542
GO:2000647
Participates
as an input of
OPTN, TBK1 bind ubiquitinated MOM proteins (Drosophila melanogaster)
as a component of
TBK1:OPTN:K63-polyUb-mitochondrial proteins [cytosol] (Drosophila melanogaster)
p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] (Drosophila melanogaster)
Other forms of this molecule
KEY [cytosol]
OPTN [recycling endosome membrane]
IKBKG [nucleoplasm]
phospho-p-S177-OPTN [nucleoplasm]
phospho-p-S177-OPTN [cytosol]
OPTN [Golgi membrane]
K63polyUb-IKBKG [cytosol]
IKBKG [cytosol]
phospho-p-S177,S473,S513-OPTN [cytosol]
Inferred From
OPTN [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_523856.2
Flybase
FBgn0041205
PRO
Q9GYV5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VEZ5 IKKbeta
8
IRD5 [cytosol]
(R-DME-206001)
Phospho IRD5 [cytosol]
(R-DME-206139)
phospho-p-Y187,Y198-CHUK [cytosol]
(R-DME-9861501)
phospho-p-T23-CHUK [cytosol]
(R-DME-198615)
phospho-p-S176,S180-CHUK [cytosol]
(R-DME-177667)
phospho-p-S177,S181-IKBKB [cytosol]
(R-DME-202506)
CHUK [cytosol]
(R-DME-168104)
IKBKB [cytosol]
(R-DME-168114)
0.632
4
UniProt:P34082
2
Fas2 [extracellular region]
(R-DME-8941043)
Fas2 [plasma membrane]
(R-DME-8940745)
0.527
2
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