Reactome | Irk2 [plasma membrane]

Irk2 [plasma membrane]

Stable Identifier

R-DME-975292-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

KCNJ15, A0A0B4LHI9

Locations in the PathwayBrowser

Expand all

Neuronal System (Drosophila melanogaster)

- Potassium Channels (Drosophila melanogaster)
  - Inwardly rectifying K+ channels (Drosophila melanogaster)
    - G protein gated Potassium channels (Drosophila melanogaster)
      - Activation of G protein gated Potassium channels (Drosophila melanogaster)
        
        Activation of GIRK/Kir3 Channels (Drosophila melanogaster)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Drosophila melanogaster)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
- Transmission across Chemical Synapses (Drosophila melanogaster)
  - Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
    - GABA receptor activation (Drosophila melanogaster)
      - GABA B receptor activation (Drosophila melanogaster)
        
        Activation of GABAB receptors (Drosophila melanogaster)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Drosophila melanogaster)
        
        Activation of GIRK/Kir3 Channels (Drosophila melanogaster)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Drosophila melanogaster)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)
        
        Kir heterotetramers [plasma membrane] (Drosophila melanogaster)
        
        Kir4.2:Kir5.1 heterotetramer [plasma membrane] (Drosophila melanogaster)
        
        Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)
        
        Irk2 [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:A0A0B4LHI9

Gene Names

Irk2

Reference Genes

BioGPS Gene:42770 Irk2

ENSEMBL:FBgn0039081

Flybase:FBgn0039081

Monarch:42770 Irk2

NCBI Gene:42770 Irk2

Reference Transcript

RefSeq:NM_001300556.1 Irk2

Other Identifiers

150448_at

152371_at

1638466_a_at

42770

GO:0005215

GO:0005242

GO:0005886

GO:0006811

GO:0006813

GO:0016020

GO:0034220

GO:0034702

GO:0034765

GO:0035220

GO:0042391

GO:0048856

GO:0055085

GO:1990573

Participates

as a member of

Homologues of KCNJ15 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

Irk2 [plasma membrane]

Inferred From

KCNJ15 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001287485.1

Flybase

FBgn0039081

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