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p-Y185,Y187 MAPK1 dimer [nucleoplasm]
Stable Identifier
R-DRE-109856
Type
Complex
Species
Danio rerio
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular Senescence (Danio rerio)
Oncogene Induced Senescence (Danio rerio)
MAPKs phosphorylate ETS1 and ETS2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Oxidative Stress Induced Senescence (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Senescence-Associated Secretory Phenotype (SASP) (Danio rerio)
MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-17 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Innate Immune System (Danio rerio)
Fc epsilon receptor (FCERI) signaling (Danio rerio)
FCERI mediated MAPK activation (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll-like Receptor Cascades (Danio rerio)
Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
MyD88-independent TLR4 cascade (Danio rerio)
TRIF (TICAM1)-mediated TLR4 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
MAPK targets/ Nuclear events mediated by MAP kinases (Danio rerio)
Activation of the AP-1 family of transcription factors (Danio rerio)
c-FOS activation by phospho ERK1/2 (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Signal Transduction (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF-independent MAPK1/3 activation (Danio rerio)
Nuclear DUSPs dephosphorylate MAPKs (Danio rerio)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Phosphorylated MAPKs translocate into the nucleus (Danio rerio)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
Negative regulation of MAPK pathway (Danio rerio)
Nuclear DUSPs dephosphorylate MAPKs (Danio rerio)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Phosphorylated MAPKs translocate into the nucleus (Danio rerio)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Extra-nuclear estrogen signaling (Danio rerio)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Danio rerio)
p-S10 CDKN1B translocates to the cytosol (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Estrogen-stimulated signaling through PRKCZ (Danio rerio)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by NTRKs (Danio rerio)
Signaling by NTRK1 (TRKA) (Danio rerio)
Nuclear Events (kinase and transcription factor activation) (Danio rerio)
ERK/MAPK targets (Danio rerio)
ERKs are inactivated (Danio rerio)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
ERKs are inactivated by protein phosphatase 2A (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
Signalling to ERKs (Danio rerio)
Prolonged ERK activation events (Danio rerio)
Frs2-mediated activation (Danio rerio)
p-T,Y MAPK dimers translocate to nucleus (Danio rerio)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
(Danio rerio)
Participates
as an output of
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Danio rerio)
as a member of
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)
This entity regulates
Positively
p-S10 CDKN1B translocates to the cytosol
(Danio rerio)
Inferred From
p-Y185,Y187 MAPK1 dimer [nucleoplasm]
(Homo sapiens)
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