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NRG1/2:p-10Y-ERBB3 [plasma membrane]
Stable Identifier
R-DRE-1248743
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs [plasma membrane] (Danio rerio)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
ERBB2 Activates PTK6 Signaling (Danio rerio)
Activated ERBB2 binds PTK6 (BRK) (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ERBB2 (Danio rerio)
Downregulation of ERBB2 signaling (Danio rerio)
Downregulation of ERBB2:ERBB3 signaling (Danio rerio)
RNF41 binds neuregulin-activated ERBB3 (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
RNF41 ubiquitinates activated ERBB3 (Danio rerio)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Danio rerio)
Heterodimers of p-ERBB2 dephosphorylated at Y1248 [plasma membrane] (Danio rerio)
Phosphorylated p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Phosphorylated p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
ERBB2 Activates PTK6 Signaling (Danio rerio)
Activated ERBB2 binds PTK6 (BRK) (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
ERBB2 Regulates Cell Motility (Danio rerio)
Phosphorylated ERBB2 heterodimers bind MEMO1 (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
PI3K events in ERBB2 signaling (Danio rerio)
Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
SHC1 events in ERBB2 signaling (Danio rerio)
SHC1 phosphorylation by ERBB2 heterodimers (Danio rerio)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Trans-autophosphorylation of ERBB2 heterodimers (Danio rerio)
p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Danio rerio)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
nrg2b [extracellular region]
(Danio rerio)
phospho-p-10Y-ERBB3-1 [plasma membrane]
(Danio rerio)
Participates
as a component of
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Danio rerio)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Danio rerio)
Inferred From
NRG1/2:p-10Y-ERBB3 [plasma membrane]
(Homo sapiens)
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