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NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane]
Stable Identifier
R-DRE-1250191
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ERBB2 (Danio rerio)
PI3K events in ERBB2 signaling (Danio rerio)
Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane]
(Danio rerio)
pik3r1 [plasma membrane]
(Danio rerio)
Participates
as a component of
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
Inferred From
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane]
(Homo sapiens)
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