Reactome | zgc:64226 [nucleoplasm]

zgc:64226 [nucleoplasm]

Stable Identifier

R-DRE-1592223

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

SP1, Q7T300

Locations in the PathwayBrowser

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Cell-Cell communication (Danio rerio)

- Cell junction organization (Danio rerio)
  - Cell-cell junction organization (Danio rerio)
    - Adherens junctions interactions (Danio rerio)
      - Regulation of Homotypic Cell-Cell Adhesion (Danio rerio)
        
        Regulation of Expression and Function of Type II Classical Cadherins (Danio rerio)
        
        Regulation of CDH11 Expression and Function (Danio rerio)
        
        Regulation of CDH11 gene transcription (Danio rerio)
        
        ZEB2 binds SP1 (Danio rerio)
        
        ZEB2:SP1 [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)

Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - RNA polymerase II transcribes snRNA genes (Danio rerio)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Danio rerio)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
    - Integrator complex processes the 3' end of snRNA (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        zgc:64226 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7T300

Gene Names

zgc:64226

Reference Genes

BioGPS Gene:387291 zgc:64226

ENSEMBL:ENSDARG00000005186

KEGG Gene (Danio rerio):387291 zgc:64226

Monarch:387291 zgc:64226

NCBI Gene:387291 zgc:64226

Reference Transcript

RefSeq:NM_200124.1 zgc:64226

Participates

as a component of

as an input of

ZEB2 binds SP1 (Danio rerio)

Other forms of this molecule

zgc:64226 [nucleoplasm]

Inferred From

SP1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_956418.1

ZFIN

ZDB-GENE-031202-3