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TRAF6 [cytosol]
Stable Identifier
R-DRE-166366
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
Q6IWL4
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
TCR signaling (Danio rerio)
Downstream TCR signaling (Danio rerio)
Auto-ubiquitination of TRAF6 (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 trimer bound to CBM complex [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Translocation of TRAF6 to CBM complex (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 trimer bound to CBM complex [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-1 family signaling (Danio rerio)
Interleukin-1 signaling (Danio rerio)
Hyperphosphorylated IRAK1 associates with TRAF6 (Danio rerio)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK1 induces oligomerisation of TRAF6 (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binding leads to IRAK1:TRAF6 release (Danio rerio)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 is K63 poly-ubiquitinated (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Danio rerio)
hp-IRAK1:3xTRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p62:MEKK3 binds to TRAF6 (Danio rerio)
MAP3K3:SQSTM1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Innate Immune System (Danio rerio)
C-type lectin receptors (CLRs) (Danio rerio)
CLEC7A (Dectin-1) signaling (Danio rerio)
K63polyUb-TRAF6 ubiquitinates TAK1 (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MALT1 oligomers (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 oligomer autoubiquitinates (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane] (Danio rerio)
TRAF6 oligomer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 oligomerizes (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane] (Danio rerio)
TRAF6 oligomer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Fc epsilon receptor (FCERI) signaling (Danio rerio)
FCERI mediated NF-kB activation (Danio rerio)
Auto-ubiquitination of TRAF6 (Danio rerio)
DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane] (Danio rerio)
CBM oligomer:TRAF6 oligomer [plasma membrane] (Danio rerio)
TRAF6 oligomer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Oligomerization of TRAF6 (Danio rerio)
DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Danio rerio)
CBM oligomer:TRAF6 [plasma membrane] (Danio rerio)
BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Danio rerio)
MALT1oligomer:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane] (Danio rerio)
CBM oligomer:TRAF6 oligomer [plasma membrane] (Danio rerio)
TRAF6 oligomer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Recruitment of TRAF6 to CBM complex by binding to MALT1 (Danio rerio)
DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Danio rerio)
CBM oligomer:TRAF6 [plasma membrane] (Danio rerio)
BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Danio rerio)
MALT1oligomer:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Danio rerio)
NOD1/2 Signaling Pathway (Danio rerio)
RIP2 induces K63-linked ubiquitination of NEMO (Danio rerio)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
RIP2 is K63 polyubiquitinated (Danio rerio)
RIP2 ubiquitin ligases [cytosol] (Danio rerio)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll-like Receptor Cascades (Danio rerio)
Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
NEMO subunit of IKK complex binds to activated IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
NEMO subunit of IKK complex binds to activated IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
NEMO subunit of IKK complex binds to activated IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
MyD88-independent TLR4 cascade (Danio rerio)
TRIF(TICAM1)-mediated TLR4 signaling (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
NEMO subunit of IKK complex binds to activated IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
IRAK1 recruits IKK complex (Danio rerio)
NEMO subunit of IKK complex binds to activated IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Pellino ubiquitinates hp-IRAK1 (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK2 mediated activation of TAK1 complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Danio rerio)
IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Regulation of NF-kappa B signaling (Danio rerio)
TRAF2,6 ubiquitinates NLRC5 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
Ovarian tumor domain proteases (Danio rerio)
OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Danio rerio)
OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Danio rerio)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Danio rerio)
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Danio rerio)
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Danio rerio)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
USP4 deubiquitinate TRAF2,TRAF6 (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Death Receptor Signaling (Danio rerio)
p75 NTR receptor-mediated signalling (Danio rerio)
Cell death signalling via NRAGE, NRIF and NADE (Danio rerio)
NRIF signals cell death from the nucleus (Danio rerio)
TRAF6 binds to p75NTR:NRIF (Danio rerio)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 polyubiquitinates NRIF (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Danio rerio)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p75NTR signals via NF-kB (Danio rerio)
NF-kB is activated and signals survival (Danio rerio)
IKKbeta is activated (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p75NTR recruits signalling complexes (Danio rerio)
IKK-beta is recruited (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
IRAK interacts with TRAF6 (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
MYD88 dissociates (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
TRAF6 is auto-ubiquitinated (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p62 is recruited and forms a complex with TRAF6 (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
p62 recruits an atypical PKC (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:aPKCi [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Danio rerio)
TRAF6 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6IWL4
Reference Genes
BioGPS Gene:554561
ENSEMBL:ENSDARG00000028058
KEGG Gene (Danio rerio):554561
Monarch:554561
NCBI Gene:554561
Reference Transcript
RefSeq:NM_001044752.1
Other Identifiers
13239599
554561
CJ003403
CJ003404
CJ003405
CJ003406
CJ007623
CJ007625
CJ007626
CJ007627
CJ007903
CJ007905
CJ007906
CJ007907
CJ009478
CJ009480
CJ009481
CJ009482
CJ009845
CJ009847
CJ009848
CJ009849
CJ010296
CJ010298
CJ010299
CJ010300
CJ010351
CJ010353
CJ010354
CJ010355
CJ010826
CJ010828
CJ010829
CJ010830
CJ010913
CJ010915
CJ010916
CJ010917
CJ011159
CJ011163
CJ011164
CJ011165
CJ012157
CJ012159
CJ012160
CJ012161
CJ013846
CJ014444
CJ014507
CUST_1753_PI424165564
CUST_1754_PI424165564
CUST_1755_PI424165564
CUST_1756_PI424165564
CUST_1757_PI424165564
CUST_1758_PI424165564
CUST_1759_PI424165564
CUST_1760_PI424165564
DRER04600
Dr.15109.1.A1_at
ENSDART00000038273
ENSDART00000038273_1
ENSDART00000038273_2
GO:0004842
GO:0005164
GO:0005515
GO:0007165
GO:0008270
GO:0012501
GO:0016567
GO:0016740
GO:0023052
GO:0036211
GO:0042981
GO:0043122
GO:0140096
GT_Spec_NM_001044752.1_250525
JP003802
JP003803
JP003804
JP003805
JP008021
JP008023
JP008024
JP008025
JP008301
JP008303
JP008304
JP008305
JP009876
JP009878
JP009879
JP009880
JP010243
JP010245
JP010246
JP010247
JP010694
JP010696
JP010697
JP010698
JP010749
JP010751
JP010752
JP010753
JP011224
JP011226
JP011227
JP011228
JP011311
JP011313
JP011314
JP011315
LOL04625
LOL04626
LOL04627
LOL04628
LOL04629
LOL04630
LOL04631
LOL04674
LOL04677
LOL04678
MADDr01007398
NM_001044752
OTTDART00000013635
TC252424
XM_692005
Participates
as a member of
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Danio rerio)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Danio rerio)
TRAF2, TRAF6 [cytosol] (Danio rerio)
as a component of
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Danio rerio)
TRAF6 homotrimer [cytosol] (Danio rerio)
MAP3K3:SQSTM1:TRAF6 [cytosol] (Danio rerio)
p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Danio rerio)
MALT1oligomer:TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:3xTRAF6 [cytosol] (Danio rerio)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Danio rerio)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
MEKK1:activated TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] (Danio rerio)
TRAF6 trimer bound to CBM complex [plasma membrane] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Danio rerio)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Danio rerio)
as an input of
Hyperphosphorylated IRAK1 associates with TRAF6 (Danio rerio)
p62:MEKK3 binds to TRAF6 (Danio rerio)
IRAK1 induces oligomerisation of TRAF6 (Danio rerio)
TRAF6 oligomerizes (Danio rerio)
TRAF6 binds MALT1 oligomers (Danio rerio)
Oligomerization of TRAF6 (Danio rerio)
Recruitment of TRAF6 to CBM complex by binding to MALT1 (Danio rerio)
TRAF6 binds MEKK1 (Danio rerio)
IRAK interacts with TRAF6 (Danio rerio)
IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Danio rerio)
Translocation of TRAF6 to CBM complex (Danio rerio)
IRAK2 induces TRAF6 oligomerization (Danio rerio)
as a repeated unit of
TRAF6 oligomer [cytosol] (Danio rerio)
Other forms of this molecule
K48polyUb-TRAF6 [cytosol]
PolyUb-TRAF6 [cytosol]
TRAF6 [endosome membrane]
K63polyUb-TRAF6 [endosome membrane]
TRAF6 [plasma membrane]
K63polyUb-TRAF6 [plasma membrane]
K63polyUb-TRAF6 [cytosol]
Inferred From
TRAF6 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001038217.1
IntEnz
2.3.2.27
ZFIN
ZDB-GENE-030131-5735
Ensembl
ENSDARP00000036715
,
ENSDARG00000028058
,
ENSDART00000191675
,
ENSDART00000038273
,
ENSDART00000180847
,
ENSDARP00000151579
,
ENSDARP00000150477
PRO
Q6IWL4
PDB
5VNZ
,
6MYD
,
5VO0
© 2023
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