Reactome | cpsf4 [nucleoplasm]

cpsf4 [nucleoplasm]

Stable Identifier

R-DRE-169104

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

CPSF4, Q98881

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - RNA Polymerase II Transcription Termination (Danio rerio)
    - Cleavage of Intronless Pre-mRNA at 3'-end (Danio rerio)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Danio rerio)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
    - Cleavage of mRNA at the 3'-end (Danio rerio)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)

Metabolism of RNA (Danio rerio)

- Processing of Capped Intron-Containing Pre-mRNA (Danio rerio)
  - mRNA 3'-end processing (Danio rerio)
    - mRNA Polyadenylation (Danio rerio)
      - Core CPA complex binds capped pre-mRNA (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - Formation of the CPSF complex (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - Formation of the core cleavage and polyadenylation complex (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - PP1 dephosphorylates RNA Pol II (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Danio rerio)
        
        CPA complex [nucleoplasm] (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        CPA complex [nucleoplasm] (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - RBBP6 activates CPSF complex (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        CPA complex [nucleoplasm] (Danio rerio)
        
        Core CPA complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Danio rerio)
        
        Ub-K63-(NEW)CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
- Processing of Capped Intronless Pre-mRNA (Danio rerio)
  - Processing of Intronless Pre-mRNAs (Danio rerio)
    - Cleavage of Intronless Pre-mRNA at 3'-end (Danio rerio)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Danio rerio)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
    - Recruitment of CstF to the CPSF Bound Pre-mRNA (Danio rerio)
      - CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)
      - CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Danio rerio)
        
        CPSF [nucleoplasm] (Danio rerio)
        
        cpsf4 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q98881

Gene Names

cpsf4

Reference Genes

BioGPS Gene:30203 cpsf4

ENSEMBL:ENSDARG00000020217

KEGG:dre:30203 cpsf4

Monarch:30203 cpsf4

NCBI Gene:30203 cpsf4

UCSC:Q98881 cpsf4

Reference Transcript

RefSeq:NM_131009.1 cpsf4

Participates

as an input of

Formation of the CPSF complex (Danio rerio)

as a component of

Inferred From

CPSF4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_571084.1

ZFIN

ZDB-GENE-990415-180

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