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TGFBR2 [plasma membrane]
Stable Identifier
R-DRE-170842
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
plasma membrane
Synonyms
Q58EQ1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Signaling by TGFB family members (Danio rerio)
Signaling by TGF-beta Receptor Complex (Danio rerio)
TGF-beta receptor signaling activates SMADs (Danio rerio)
Activated type I receptor phosphorylates SMAD2/3 directly (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
CBL binds TGFBR2 (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2:CBL [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Dimeric TGF-beta-1 binds to the receptor (Danio rerio)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Downregulation of TGF-beta receptor signaling (Danio rerio)
BAMBI interferes with the interaction of type I receptor with type II receptor (Danio rerio)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Degradation of TGF-beta receptor complex (Danio rerio)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Danio rerio)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Phosphorylated SMAD2/3 dissociates from TGFBR (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 phosphorylates TGFBR1 (Danio rerio)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 recruits TGFBR1 (Danio rerio)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Danio rerio)
Disassembly of tight junctions (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
SMURF1 binds phosphorylated PARD6A (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
SMURF1 ubiquitinates RHOA (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Danio rerio)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Danio rerio)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
TGFBR2 [plasma membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:Q58EQ1
Reference Genes
BioGPS Gene:30739
CTD Gene:30739
ENSEMBL:ENSDARG00000034541
KEGG Gene (Danio rerio):30739
Monarch:30739
NCBI Gene:30739
Reference Transcript
RefSeq:NM_182855.3
Participates
as an input of
CBL binds TGFBR2 (Danio rerio)
Dimeric TGF-beta-1 binds to the receptor (Danio rerio)
as a component of
TGFBR2:CBL [plasma membrane] (Danio rerio)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Danio rerio)
TGFBR2 homodimer [plasma membrane] (Danio rerio)
Inferred From
TGFBR2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_878275.2
ZFIN
ZDB-GENE-980526-375
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