Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p4hb [endoplasmic reticulum lumen]
Stable Identifier
R-DRE-174692
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
endoplasmic reticulum lumen
Synonyms
P4HB, A0A0R4IPV5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
GPX7,8 catalyze peroxidation of P4HB (PDI) (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Extracellular matrix organization (Danio rerio)
Collagen formation (Danio rerio)
Collagen biosynthesis and modifying enzymes (Danio rerio)
P4HB binds Collagen chains (Danio rerio)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
P4HB:4-Hyp collagen propeptides dissociates (Danio rerio)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Danio rerio)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-12 family signaling (Danio rerio)
Interleukin-12 signaling (Danio rerio)
IL12B dimerizes (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Metabolism of proteins (Danio rerio)
Peptide hormone metabolism (Danio rerio)
Insulin processing (Danio rerio)
P4HB mediates disulfide bond formation in Proinsulin (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
Autoproteolytic cleavage of Hh precursors (Danio rerio)
NglycoAsn-Hh precursors:P4HB [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
P4HB forms mixed disulphides with Hh precursors (Danio rerio)
NglycoAsn-Hh precursors:P4HB [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
Transport of small molecules (Danio rerio)
Plasma lipoprotein assembly, remodeling, and clearance (Danio rerio)
Plasma lipoprotein remodeling (Danio rerio)
LDL remodeling (Danio rerio)
MTTP binds lomitapide (Danio rerio)
MTTP:PDI:lipid complex [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
MTTP:lomitapide [endoplasmic reticulum lumen] (Danio rerio)
MTTP:PDI:lipid complex [endoplasmic reticulum lumen] (Danio rerio)
p4hb [endoplasmic reticulum lumen] (Danio rerio)
External Reference Information
External Reference
UniProt:A0A0R4IPV5
Gene Names
p4hb
Reference Genes
BioGPS Gene:406673 p4hb
ENSEMBL:ENSDARG00000105116
ENSEMBL:ENSDARG00000105116.2 p4hb
ENSEMBL:ENSDARG00000116847.1 p4hb
KEGG Gene (Danio rerio):406673 p4hb
Monarch:406673 p4hb
NCBI Gene:406673 p4hb
Reference Transcript
RefSeq:NM_213364.3 p4hb
Other Identifiers
13213120
406673
A_15_P416710
A_15_P744008
CUST_10860_PI428451958
DRER16300
ENSDART00000074477_1
ENSDART00000074477_2
ENSDART00000103124
GT_Spec_NM_213364.3_215815
GT_Xhyb_XM_005166180.1_192095
LOLS02893
LOLS14154
MADDr01014099
NM_213364
OTTDART00000013518
Participates
as an output of
P4HB mediates disulfide bond formation in Proinsulin (Danio rerio)
P4HB:4-Hyp collagen propeptides dissociates (Danio rerio)
Autoproteolytic cleavage of Hh precursors (Danio rerio)
as an input of
P4HB binds Collagen chains (Danio rerio)
P4HB forms mixed disulphides with Hh precursors (Danio rerio)
GPX7,8 catalyze peroxidation of P4HB (PDI) (Danio rerio)
as a component of
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Danio rerio)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Danio rerio)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Danio rerio)
NglycoAsn-Hh precursors:P4HB [endoplasmic reticulum lumen] (Danio rerio)
MTTP:PDI:lipid complex [endoplasmic reticulum lumen] (Danio rerio)
Other forms of this molecule
p4hb [endoplasmic reticulum lumen]
Inferred From
P4HB [endoplasmic reticulum lumen]
(Homo sapiens)
Cross References
RefSeq
NP_998529.3
ZFIN
ZDB-GENE-080610-1
Ensembl
ENSDART00000169035
,
ENSDARG00000116847
,
ENSDARG00000105116
,
ENSDARP00000138657
,
ENSDARP00000136475
,
ENSDART00000167937
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text