Reactome | cul5 [cytosol]

cul5 [cytosol]

Stable Identifier

R-DRE-180528

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

CUL5, F1REN0

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Class I MHC mediated antigen processing & presentation (Danio rerio)
    - Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
      - Interaction of E3 with substrate and E2-Ub complex (Danio rerio)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
      - Polyubiquitination of substrate (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3:Ub:substrate [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
      - Release of E3 from polyubiquitinated substrate (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
      - Transfer of Ub from E2 to substrate and release of E2 (Danio rerio)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        E3:Ub:substrate [cytosol] (Danio rerio)
        
        E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
        
        RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
        
        Cul5-SCF complex [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
        
        cul5 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:F1REN0

Gene Names

cul5

Reference Genes

BioGPS Gene:327215 cul5

CTD Gene:327215 cul5

ENSEMBL:ENSDARG00000069742

ENSEMBL:ENSDARG00000069742.6 cul5

ENSEMBL:ENSDARG00000112542.1 cul5

ENSEMBL:ENSDARG00000116292.1 cul5

KEGG Gene (Danio rerio):327215 cul5

Monarch:327215 cul5

NCBI Gene:327215 cul5

Reference Transcript

RefSeq:NM_001328059.1 cul5

Other Identifiers

13024572

327215

A_15_P105842

A_15_P639661

A_15_P658076

CJ012095

CJ012097

CUST_2937_PI428451953

DRER18376

Dr.10370.1.S1_at

ENSDART00000110111

GO:0006511

GO:0016567

GO:0019005

GO:0030163

GO:0030674

GO:0031146

GO:0031461

GO:0031466

GO:0031625

GO:0036211

GO:0048856

GO:0060090

GT_Xhyb_XM_005161006.1_101031

LOLS08331

TC250830

ZV700S00000123

Participates

as a component of

Other forms of this molecule

cul5 [cytosol]

Inferred From

CUL5 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001314988.1

ZFIN

ZDB-GENE-030131-5426

Ensembl

ENSDARP00000150867, ENSDART00000110111, ENSDART00000188296, ENSDART00000190789, ENSDARG00000069742, ENSDARP00000100474, ENSDARP00000157577, ENSDARG00000116292, ENSDARG00000112542

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