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CDC42:GTP [plasma membrane]
Stable Identifier
R-DRE-182921
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPHB-mediated forward signaling (Danio rerio)
CDC42 and PIP2 bind WASL, activating it (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
N-WASP binds ARP2/3 and G-actin (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Netrin-1 signaling (Danio rerio)
DCC mediated attractive signaling (Danio rerio)
Activation of Cdc42 (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Recruitment and activation of N-WASP by Cdc42 (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Costimulation by the CD28 family (Danio rerio)
CD28 co-stimulation (Danio rerio)
CD28 dependent Vav1 pathway (Danio rerio)
Activation of PAKs by RAC1 and CDC42 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Innate Immune System (Danio rerio)
Fcgamma receptor (FCGR) dependent phagocytosis (Danio rerio)
Regulation of actin dynamics for phagocytic cup formation (Danio rerio)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Danio rerio)
Mother filament:branching complex [cytosol] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Detachment of WASP/WAVE (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Mother filament:branching complex [cytosol] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK6/MAPK4 signaling (Danio rerio)
Activation of PAKs by RAC1 and CDC42 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
CDC42:GTP binds PAK2 (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
FYN phosphorylates PAK2 (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK2 autophorylates (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
p38 MAPK activation by VEGFR (Danio rerio)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Danio rerio)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate WASPs and WAVEs (Danio rerio)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Danio rerio)
Mother filament:branching complex [cytosol] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Detachment of WASP/WAVE (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
Mother filament:branching complex [cytosol] (Danio rerio)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RHO GTPases activate IQGAPs (Danio rerio)
GTP-bound RAC1 and CDC42 bind IQGAPs (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
IQGAPs bind F-actin, which is inhibited by calmodulin (Danio rerio)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RHO GTPases activate PAKs (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RAC1 and CDC42 activate PAK2 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
RHO GTPase cycle (Danio rerio)
CDC42 GTPase cycle (Danio rerio)
CDC42 GAPs stimulate CDC42 GTPase activity (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
CDC42 GEFs activate CDC42 (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
CDC42 translocates to the endoplasmic reticulum membrane (Danio rerio)
CDC42:GTP [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
cdc42 [plasma membrane]
(Danio rerio)
GTP [cytosol]
Participates
as an input of
CDC42 translocates to the endoplasmic reticulum membrane (Danio rerio)
CDC42 GAPs stimulate CDC42 GTPase activity (Danio rerio)
CDC42:GTP binds PAK2 (Danio rerio)
as an output of
CDC42 GEFs activate CDC42 (Danio rerio)
as a component of
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
PAK2 dimer:CDC42:GTP [plasma membrane] (Danio rerio)
Beta-Pix:CDC42:GTP [cytosol] (Danio rerio)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Danio rerio)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Danio rerio)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
as a member of
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
Inferred From
CDC42:GTP [plasma membrane]
(Homo sapiens)
CDC42:GTP [plasma membrane]
(Homo sapiens)
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