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pdgfab [extracellular region]
Stable Identifier
R-DRE-184199
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
extracellular region
Synonyms
PDGFA-1, Q08CD2
Locations in the PathwayBrowser
Expand all
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Response to elevated platelet cytosolic Ca2+ (Danio rerio)
Platelet degranulation (Danio rerio)
Exocytosis of platelet alpha granule contents (Danio rerio)
Platelet alpha granule contents [extracellular region] (Danio rerio)
PDGF dimer [extracellular region] (Danio rerio)
PDGF AB heterodimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by PDGF (Danio rerio)
Autophosphorylation of PDGF alpha receptors (Danio rerio)
PDGF:PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Danio rerio)
PDGF:PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Downstream signal transduction (Danio rerio)
Activated PLC gamma dissociates from the PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Activation of Src (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Crk binds to the active PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
GRB2:SOS1 complex binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Nck binds to the active PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PI3-kinase binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PLC-gamma binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
Phosphorylation of PLCgamma by PDGFR (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
SH2 domain of Src binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
STAT binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF dimer binds two receptors simultaneously (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF:PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGF-AA clevage by Furin (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGFRs bind type I TKI (Danio rerio)
PDGF:PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Danio rerio)
PDGF:PDGF receptor dimer [plasma membrane] (Danio rerio)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
pdgfab [extracellular region] (Danio rerio)
External Reference Information
External Reference
UniProt:Q08CD2
Gene Names
pdgfab
Reference Genes
BioGPS Gene:767790 pdgfab
CTD Gene:767790 pdgfab
ENSEMBL:ENSDARG00000098578
KEGG Gene (Danio rerio):767790 pdgfab
Monarch:767790 pdgfab
NCBI Gene:767790 pdgfab
Reference Transcript
RefSeq:NM_001076757.1 pdgfab
Participates
as a component of
PDGF AB heterodimer [extracellular region] (Danio rerio)
active PDGF-AA dimer [extracellular region] (Danio rerio)
as a member of
PDGF A and B chains with retention motif [extracellular region] (Danio rerio)
Other forms of this molecule
pdgfab [platelet alpha granule lumen]
pdgfab [endoplasmic reticulum lumen]
pdgfab [endoplasmic reticulum lumen]
pdgfab [Golgi lumen]
pdgfab [Golgi membrane]
pdgfab [Golgi membrane]
pdgfab [extracellular region]
Inferred From
Active platelet-derived growth factor A chain isoforms [extracellular region]
(Homo sapiens)
PDGFA-1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_001070225.1
ZFIN
ZDB-GENE-060929-124
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