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PDGF:Phospho-PDGF receptor dimer [plasma membrane]
Stable Identifier
R-DRE-186811
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by PDGF (Danio rerio)
Autophosphorylation of PDGF alpha receptors (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Downstream signal transduction (Danio rerio)
Activated PLC gamma dissociates from the PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Activation of Src (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Crk binds to the active PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
GRB2:SOS1 complex binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Nck binds to the active PDGF receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PI3-kinase binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PLC-gamma binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
Phosphorylation of PLCgamma by PDGFR (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
SH2 domain of Src binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
STAT binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Active PDGF dimers (AA, AB, BB) [extracellular region]
(Danio rerio)
Phospho-alpha receptor homodimer [plasma membrane]
(Danio rerio)
Participates
as an input of
Nck binds to the active PDGF receptor (Danio rerio)
SH2 domain of Src binds to the active receptor (Danio rerio)
Crk binds to the active PDGF receptor (Danio rerio)
STAT binds to the active receptor (Danio rerio)
PI3-kinase binds to the active receptor (Danio rerio)
PLC-gamma binds to the active receptor (Danio rerio)
GRB2:SOS1 complex binds to the active receptor (Danio rerio)
as a component of
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Danio rerio)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Danio rerio)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
as an output of
Activated PLC gamma dissociates from the PDGF receptor (Danio rerio)
Autophosphorylation of PDGF alpha receptors (Danio rerio)
Inferred From
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane]
(Homo sapiens)
PDGF:Phospho-PDGF receptor dimer [plasma membrane]
(Homo sapiens)
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