Reactome | ywhae1 [cytosol]

ywhae1 [cytosol]

Stable Identifier

R-DRE-194368

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

YWHAE, Q7ZW20

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - Generic Transcription Pathway (Danio rerio)
    - Transcriptional Regulation by TP53 (Danio rerio)
      - TP53 Regulates Metabolic Genes (Danio rerio)
        
        DDIT4 binds 14-3-3 dimer (Danio rerio)
        
        14-3-3 dimer [cytosol] (Danio rerio)
        
        YWHAE dimer [cytosol] (Danio rerio)
        
        ywhae1 [cytosol] (Danio rerio)
        
        DDIT4:14-3-3 dimer [cytosol] (Danio rerio)
        
        14-3-3 dimer [cytosol] (Danio rerio)
        
        YWHAE dimer [cytosol] (Danio rerio)
        
        ywhae1 [cytosol] (Danio rerio)

Programmed Cell Death (Danio rerio)

- Apoptosis (Danio rerio)
  - Intrinsic Pathway for Apoptosis (Danio rerio)
    - Activation of BH3-only proteins (Danio rerio)
      - Activation of BAD and translocation to mitochondria (Danio rerio)
        
        Sequestration of BAD protein by 14-3-3 (Danio rerio)
        
        14-3-3 dimer [cytosol] (Danio rerio)
        
        YWHAE dimer [cytosol] (Danio rerio)
        
        ywhae1 [cytosol] (Danio rerio)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Danio rerio)
        
        14-3-3 dimer [cytosol] (Danio rerio)
        
        YWHAE dimer [cytosol] (Danio rerio)
        
        ywhae1 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZW20

Gene Names

ywhae1

Reference Genes

BioGPS Gene:322060 ywhae1

CTD Gene:322060 ywhae1

ENSEMBL:ENSDARG00000006399

KEGG:dre:322060 ywhae1

Monarch:322060 ywhae1

NCBI Gene:322060 ywhae1

UCSC:Q7ZW20 ywhae1

Reference Transcript

RefSeq:NM_212605.2 ywhae1

Other Identifiers

13020381

322060

A_15_P165486

A_15_P207246

A_15_P512787

A_15_P623996

BC045325

CJ012415

CJ014352

CUST_2250_PI428451958

CUST_4964_PI428451953

DRER04017

DRER44441

Dr.1412.1.S1_at

Dr.1412.1.S2_at

ENSDART00000032306

ENSDART00000032306_1

ENSDART00000032306_2

GO:0003824

GO:0004497

GO:0005737

GO:0007165

GO:0007346

GO:0008104

GO:0016491

GO:0050815

GT_Spec_NM_212605.2_379615

LOL00266

LOL01266

LOL01802

LOL03600

LOL03601

LOL03602

LOL03603

LOL03604

LOL03605

LOL03606

LOL03607

LOL05109

LOLS15680

MADDr01007612

NM_212605

OTTDART00000026099

OTTDART00000026100

Participates

as a component of

YWHAE dimer [cytosol] (Danio rerio)

Inferred From

YWHAE [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_997770.1

ENSEMBL

ENSDARP00000032575, ENSDART00000184458, ENSDART00000032306, ENSDART00000189061, ENSDARP00000157541, ENSDARP00000155559

ZFIN

ZDB-GENE-030131-779

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