Reactome | pfn2 [cytosol]

pfn2 [cytosol]

Stable Identifier

R-DRE-203081-3

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

PFN1, Q802D5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
  - Signaling by Rho GTPases (Danio rerio)
    - RHO GTPase Effectors (Danio rerio)
      - RHO GTPases Activate Formins (Danio rerio)
        
        Association of profilin with monomeric actin (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        Profilin:G-actin [cytosol] (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Danio rerio)
        
        RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
        
        Profilin:G-actin [cytosol] (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
        
        RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
        
        Profilin:G-actin [cytosol] (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Danio rerio)
        
        Profilin:G-actin [cytosol] (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
        
        RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
        
        Profilin:G-actin [cytosol] (Danio rerio)
        
        PFN [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
- Signaling by WNT (Danio rerio)
  - Beta-catenin independent WNT signaling (Danio rerio)
    - PCP/CE pathway (Danio rerio)
      - DAAM1 recruits PFN1 (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)
        
        ppDVL:DAAM1:PFN1 [cytosol] (Danio rerio)
        
        Homologues of PFN1 [cytosol] (Danio rerio)
        
        pfn2 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q802D5

Gene Names

pfn2

Reference Genes

BioGPS Gene:394235 pfn2

ENSEMBL:ENSDARG00000003952

ENSEMBL:ENSDARG00000003952.12 pfn2

KEGG Gene (Danio rerio):394235 pfn2

Monarch:394235 pfn2

NCBI Gene:394235 pfn2

Reference Transcript

RefSeq:NM_201336.1 pfn2

Other Identifiers

13130049

394235

A_15_P139851

A_15_P347545

A_15_P637196

A_15_P737051

BC067152

CUST_4396_PI428451958

DRER16854

Dr.1150.1.S1_at

ENSDART00000004557

ENSDART00000104687

ENSDART00000115073

GO:0003779

GO:0005737

GO:0007010

GO:0008092

GO:0030036

GO:0030833

GO:0032233

GO:0065003

GO:0071840

GT_Spec_NM_201336.1_170486

MADDr01000186

OTTDART00000023576

OTTDART00000023577

Participates

as a member of

Homologues of PFN1 [cytosol] (Danio rerio)

Inferred From

PFN1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_958493.1

ZFIN

ZDB-GENE-040115-4

Ensembl

ENSDARP00000095458, ENSDARG00000003952, ENSDART00000104687

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