Reactome | col4a5 [extracellular region]

col4a5 [extracellular region]

Stable Identifier

R-DRE-2127335

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

3x4Hyp-3Hyp-GalHyl-COL4A5, B0UXF7

Locations in the PathwayBrowser

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Extracellular matrix organization (Danio rerio)

- Collagen formation (Danio rerio)
  - Assembly of collagen fibrils and other multimeric structures (Danio rerio)
    - Crosslinking of collagen fibrils (Danio rerio)
      - Collagen type IV sulfilimine cross-linking by peroxidasin (Danio rerio)
        
        Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV networks with sulfilimine cross-links [extracellular region] (Danio rerio)
        
        Sulfilimine-containing collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens with or without sulfilimine cross-links [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) with or without sulfilimine cross-links [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Sulfilimine-containing collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) with or without sulfilimine cross-links [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
    - Formation of collagen networks (Danio rerio)
      - Collagen networks [extracellular region] (Danio rerio)
        
        Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
      - Network forming tropocollagens [extracellular region] (Danio rerio)
        
        Tropocollagen type IV [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
- Degradation of the extracellular matrix (Danio rerio)
  - Collagen degradation (Danio rerio)
    - Collagen type IV degradation by MMP2,3,4,9,10,12 (Danio rerio)
      - Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
- FN1 binds Collagen types I-V, VII (Danio rerio)
  - Collagen types I-V, VII [extracellular region] (Danio rerio)
    - Collagen IV [extracellular region] (Danio rerio)
      - Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
      - Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
  - FN1(32-2386):Collagen types I-V, VII [extracellular region] (Danio rerio)
    - Collagen types I-V, VII [extracellular region] (Danio rerio)
      - Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
- Integrin cell surface interactions (Danio rerio)
  - Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Danio rerio)
    - Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Danio rerio)
      - Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
    - Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Danio rerio)
      - Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Danio rerio)
        
        Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
- Laminin interactions (Danio rerio)
  - Laminins:Nidogens binds collagen type IV networks (Danio rerio)
    - Collagen IV [extracellular region] (Danio rerio)
      - Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
      - Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
    - Laminins with gamma-1, gamma-3:Nidogens:Collagen type IV network [extracellular region] (Danio rerio)
      - Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
- Non-integrin membrane-ECM interactions (Danio rerio)
  - DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Danio rerio)
    - Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Danio rerio)
      - Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
    - DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils [plasma membrane] (Danio rerio)
      - Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Danio rerio)
        
        Collagen IV [extracellular region] (Danio rerio)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)
        
        Collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Danio rerio)
        
        Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Danio rerio)
        
        col4a5 [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:B0UXF7 col4a5

Gene Names

col4a5

Reference Genes

ENSEMBL:ENSDARG00000052063 col4a5

Other Identifiers

13231208

323561

A_15_P100537

A_15_P144876

A_15_P484155

A_15_P516442

A_15_P674316

CUST_20038_PI428451953

CUST_5159_PI428451958

DRER09948

DRER17618

Dr.23827.1.A1_at

Dr.23827.1.A1_s_at

ENSDART00000073827

ENSDART00000073827_1

ENSDART00000073827_2

GO:0000902

GO:0003674

GO:0005198

GO:0005201

GO:0005575

GO:0005576

GO:0005581

GO:0005604

GO:0005615

GO:0007412

GO:0008150

GO:0016020

GO:0030154

GO:0030198

GO:0030312

GO:0031012

GO:0031290

GO:0032991

GO:0040007

GO:0040011

GO:0048846

GO:0048856

GO:0071711

GO:0110165

GT_Spec_XM_005166502.1_38821

GT_Xhyb_NM_001123230.1_96291

MADDr01003213

TC250089

XM_683696

ZV700S00004032

Participates

as a component of

Other forms of this molecule

col4a5 [endoplasmic reticulum lumen]

col4a5 [extracellular region]

Col4a5 [extracellular region]

col4a5 [extracellular region]

Inferred From

Collagen alpha-5(IV) chains [extracellular region] (Homo sapiens)

3x4Hyp-3Hyp-GalHyl-COL4A5 [extracellular region] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-galactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-galactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.

Cross References

Ensembl

ENSDART00000073827, ENSDARP00000068317, ENSDARG00000052063

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