Reactome | phospho-fcer1g [plasma membrane]

phospho-fcer1g [plasma membrane]

Stable Identifier

R-DRE-2454244

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

p-Y65-FCER1G, A0A0R4IN58

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Innate Immune System (Danio rerio)
  - Fc epsilon receptor (FCERI) signaling (Danio rerio)
    - FCERI mediated Ca+2 mobilization (Danio rerio)
      - Phosphorylation of TEC kinases by p-SYK (Danio rerio)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Danio rerio)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI [plasma membrane] (Danio rerio)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)
        
        phospho-fcer1g [plasma membrane] (Danio rerio)
    - FCERI mediated MAPK activation (Danio rerio)
      - Phosphorylation of SHC by SYK kinase (Danio rerio)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Danio rerio)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI [plasma membrane] (Danio rerio)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)
        
        phospho-fcer1g [plasma membrane] (Danio rerio)
    - FCERI mediated NF-kB activation (Danio rerio)
      - Phosphorylation of PKC-theta (Danio rerio)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI [plasma membrane] (Danio rerio)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)
        
        phospho-fcer1g [plasma membrane] (Danio rerio)
    - Recruitment of SYK to p-FCERI gamma subunit (Danio rerio)
      - Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI [plasma membrane] (Danio rerio)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)
        
        phospho-fcer1g [plasma membrane] (Danio rerio)
      - Clustered p:LYN:p-FCERI:IgE:allergen:SYK [plasma membrane] (Danio rerio)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI aggregate [plasma membrane] (Danio rerio)
        
        p-FCERI [plasma membrane] (Danio rerio)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)
        
        phospho-fcer1g [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4IN58

Gene Names

fcer1g

Reference Genes

BioGPS Gene:100101464 fcer1g

ENSEMBL:ENSDARG00000103276

KEGG Gene (Danio rerio):100101464 fcer1g

Monarch:100101464 fcer1g

NCBI Gene:100101464 fcer1g

Reference Transcript

RefSeq:NM_001100106.2 fcer1g

Other Identifiers

100101464

13235526

13235528

A_15_P163371

GO:0002376

GO:0003674

GO:0005575

GO:0005886

GO:0007165

GO:0007166

GO:0008150

GO:0016020

GO:0016021

GO:0019767

GO:0032991

GO:0032998

GO:0038095

GT_Spec_NM_001100106.1_310065

LOLT00125

Participates

as a component of

p-Y65,Y76-FCERIG dimer [plasma membrane] (Danio rerio)

Other forms of this molecule

fcer1g [tertiary granule membrane]

fcer1g [ficolin-1-rich granule membrane]

fcer1g [plasma membrane]

phospho-fcer1g [plasma membrane]

Inferred From

p-Y65-FCER1G [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 65 (in Homo sapiens)

Coordinate

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001093576.2

Ensembl

ENSDART00000158796, ENSDARP00000135308, ENSDARG00000103276