Reactome | trio [cytosol]

trio [cytosol]

Stable Identifier

R-DRE-2980605

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

TRIO, Q1LUA6

Locations in the PathwayBrowser

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Developmental Biology (Danio rerio)

- Nervous system development (Danio rerio)
  - Axon guidance (Danio rerio)
    - Netrin-1 signaling (Danio rerio)
      - DCC mediated attractive signaling (Danio rerio)
        
        Activation of Cdc42 (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        Activation of Rac1 (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        Recruitment and activation of N-WASP by Cdc42 (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        RhoGTPase GEF's recruited to DCC (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Danio rerio)
        
        DOCK1,TRIO [cytosol] (Danio rerio)
        
        trio [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q1LUA6

Gene Names

trio

Reference Genes

ENSEMBL:ENSDARG00000019426

UCSC:Q1LUA6 trio

Participates

as a member of

as a candidate of

CDC42 GEFs [cytosol] (Danio rerio)

as an input of

G alpha (q) binds to Trio family RhoGEFs (Danio rerio)

as a component of

G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Danio rerio)

Inferred From

RHOG GEFs [cytosol] (Homo sapiens)

RAC3 GEFs [cytosol] (Homo sapiens)

TRIO family RhoGEFs [cytosol] (Homo sapiens)

TRIO [cytosol] (Homo sapiens)

Cross References

ZFIN

ZDB-GENE-060503-334

PRO

Q1LUA6