Reactome | cdc42l2 [plasma membrane]

cdc42l2 [plasma membrane]

Stable Identifier

R-DRE-449545

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

CDC42, A3QJU6

Locations in the PathwayBrowser

Expand all

Developmental Biology (Danio rerio)

- Myogenesis (Danio rerio)
  - Nuclear translocation of p38 MAPK (Danio rerio)
    - ABL1:JLP:CDO complex [plasma membrane] (Danio rerio)
      - Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Danio rerio)
        
        Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)
    - pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Danio rerio)
      - ABL1:JLP:CDO complex [plasma membrane] (Danio rerio)
        
        Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Danio rerio)
        
        Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)
- Nervous system development (Danio rerio)
  - Axon guidance (Danio rerio)
    - EPH-Ephrin signaling (Danio rerio)
      - EPHB-mediated forward signaling (Danio rerio)
        
        CDC42 and PIP2 bind WASL, activating it (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)
        
        N-WASP binds ARP2/3 and G-actin (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
        
        CDC42:GTP [plasma membrane] (Danio rerio)
        
        cdc42l2 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A3QJU6

Gene Names

cdc42l2

Reference Genes

ENSEMBL:ENSDARG00000057869

Reference Transcript

RefSeq:XM_017353578.1 cdc42l2

Other Identifiers

13138761

556226

A_15_P120900

CUST_7960_PI428451958

DRER41203

ENSDART00000080619

ENSDART00000080619_1

ENSDART00000080619_2

GO:0003674

GO:0003924

GO:0005525

GO:0043167

GT_Xhyb_NM_001039923.1_68701

GT_Xhyb_XM_005162075.1_358795

LOL00209

LOL01209

LOL01745

LOL03277

LOL03278

LOL03279

LOL03280

LOL03281

LOL05053

MADDr01011545

NM_001039923

OTTDART00000023666

Participates

as a candidate of

as a component of

as an input of

CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Danio rerio)

Other forms of this molecule

cdc42l2 [endoplasmic reticulum membrane]

cdc42l2 [cytosol]

Inferred From

CDC42 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017209067.1

Ensembl

ENSDARP00000123487, ENSDART00000142546, ENSDARG00000057869

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