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IQGAP1 [cytosol]
Stable Identifier
R-DRE-5626371
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
E7FBD5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
MAP2K and MAPK activation (Danio rerio)
Dissociation of RAS:RAF complex (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
Dual mechanism MAPK inhibitors bind MAPKs (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
MAP2Ks and MAPKs bind to the activated RAF complex (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
MAP2Ks phosphorylate MAPKs (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAF phosphorylates MAP2K dimer (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases activate IQGAPs (Danio rerio)
GTP-bound RAC1 and CDC42 bind IQGAPs (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Danio rerio)
CDH1 dimer:CTTNB1:CTTNA1:IQGAP1:MEN1 [plasma membrane] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
IQGAPs bind CALM1 (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
IQGAPs bind F-actin, which is inhibited by calmodulin (Danio rerio)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
IQGAP [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHO GTPase cycle (Danio rerio)
CDC42 GTPase cycle (Danio rerio)
CDC42 binds effectors at the plasma membrane (Danio rerio)
CDC42 effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
CDC42:GTP:CDC42 effectors [plasma membrane] (Danio rerio)
CDC42 effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1 GTPase cycle (Danio rerio)
RAC1 binds effectors at the plasma membrane (Danio rerio)
RAC1 effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC1:GTP:RAC1 effectors [plasma membrane] (Danio rerio)
RAC1 effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC2 GTPase cycle (Danio rerio)
RAC2 binds effectors at the plasma membrane (Danio rerio)
RAC2 plasma membrane effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Danio rerio)
RAC2 plasma membrane effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOA GTPase cycle (Danio rerio)
RHOA binds effectors at the plasma membrane (Danio rerio)
RHOA plasma membrane effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Danio rerio)
RHOA plasma membrane effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOC GTPase cycle (Danio rerio)
RHOC binds effectors at the plasma membrane (Danio rerio)
RHOC effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOC:GTP:RHOC effectors [plasma membrane] (Danio rerio)
RHOC effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOQ GTPase cycle (Danio rerio)
RHOQ binds effectors at the plasma membrane (Danio rerio)
RHOQ effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Danio rerio)
RHOQ effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOU GTPase cycle (Danio rerio)
RHOU binds effectors at the plasma membrane (Danio rerio)
RHOU effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOU:GTP:RHOU effectors [plasma membrane] (Danio rerio)
RHOU effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOV GTPase cycle (Danio rerio)
RHOV binds effectors at the plasma membrane (Danio rerio)
RHOV effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
RHOV:GTP:RHOV effectors [plasma membrane] (Danio rerio)
RHOV effectors [cytosol] (Danio rerio)
IQGAP1 dimer [cytosol] (Danio rerio)
IQGAP1 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:E7FBD5
Reference Genes
ENSEMBL:ENSDARG00000078888
Other Identifiers
100002928
13239817
13301156
A_15_P337610
A_15_P391180
A_15_P406260
A_15_P413375
A_15_P494487
CUST_19988_PI428451953
CUST_337_PI424165604
CUST_338_PI424165604
CUST_339_PI424165604
CUST_340_PI424165604
CUST_341_PI424165604
CUST_342_PI424165604
CUST_343_PI424165604
DRER18469
Dr.17687.1.A1_at
ENSDART00000110283
GO:0005515
GO:0043087
GT_Spec_XM_001920812.4_374855
ZV700S00002577
Participates
as a component of
IQGAP1 dimer [cytosol] (Danio rerio)
as a candidate of
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Other forms of this molecule
IQGAP1 [plasma membrane]
IQGAP1 [secretory granule membrane]
Inferred From
IQGAP1 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSDARG00000078888
,
ENSDART00000110283
,
ENSDARP00000098704
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