Reactome | (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle]

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle]

Stable Identifier

R-DRE-5689731-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

COPII-coated ER to Golgi transport vesicle

Synonyms

A0A2R8PZC2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Danio rerio)

- Post-translational protein modification (Danio rerio)
  - Asparagine N-linked glycosylation (Danio rerio)
    - Transport to the Golgi and subsequent modification (Danio rerio)
      - ER to Golgi Anterograde Transport (Danio rerio)
        
        COPII-mediated vesicle transport (Danio rerio)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Danio rerio)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        CSNK1D phosphorylates SEC23 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Nucleotide exchange on RAB1 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)

Vesicle-mediated transport (Danio rerio)

- Membrane Trafficking (Danio rerio)
  - ER to Golgi Anterograde Transport (Danio rerio)
    - COPII-mediated vesicle transport (Danio rerio)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Danio rerio)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
      - COPII coat binds TRAPPCII and RAB1:GDP (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
      - CSNK1D phosphorylates SEC23 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
      - Nucleotide exchange on RAB1 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Danio rerio)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)
        
        (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A2R8PZC2

Reference Genes

ENSEMBL:ENSDARG00000113015

Other Identifiers

110439158

13195208

A_15_P682291

CUST_21405_PI428451953

DRER18969

DRER47898

ENSDART00000051470_y_1

ENSDART00000111180

GO:0004867

GO:0005576

GO:0005615

GO:0098772

XM_679525

Participates

as a member of

Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Danio rerio)

Other forms of this molecule

SERPINA1 [platelet alpha granule lumen]

SERPINA3 [platelet alpha granule lumen]

SERPINA4 [extracellular region]

SERPINA4 [platelet dense granule lumen]

SERPINA6 [extracellular region]

SERPINA5 [extracellular region]

SERPINA3 [secretory granule lumen]

SERPINA3 [extracellular region]

SERPINA3 [azurophil granule lumen]

SERPINA1 [extracellular region]

SERPINA1 [ficolin-1-rich granule lumen]

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen]

phospho-p-SERPINA1 [endoplasmic reticulum lumen]

SERPINA1 [endoplasmic reticulum lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

Ensembl

ENSDARP00000145378, ENSDART00000191553, ENSDARG00000113015

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