Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ddb2 [nucleoplasm]
Stable Identifier
R-DRE-5696654
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
PAR-DDB2, Q2YDS1
Locations in the PathwayBrowser
Expand all
DNA Repair (Danio rerio)
Nucleotide Excision Repair (Danio rerio)
Global Genome Nucleotide Excision Repair (GG-NER) (Danio rerio)
DNA Damage Recognition in GG-NER (Danio rerio)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
Dual Incision in GG-NER (Danio rerio)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Danio rerio)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
Formation of Incision Complex in GG-NER (Danio rerio)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Danio rerio)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Danio rerio)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
CHD1L is recruited to GG-NER site (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
TFIIH binds GG-NER site to form a verification complex (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Danio rerio)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Danio rerio)
PAR-UV-DDB [nucleoplasm] (Danio rerio)
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
ddb2 [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:Q2YDS1
Gene Names
ddb2
Reference Genes
ENSEMBL:ENSDARG00000041140
UCSC:Q2YDS1 ddb2
Other Identifiers
100004133
13057951
13057965
A_15_P207021
A_15_P348955
A_15_P767456
CJ003879
CUST_4790_PI428451953
CUST_4791_PI428451953
CUST_9727_PI428451958
DRER08137
DRER15451
DRER46034
Dr.25576.1.A1_at
ENSDART00000060302
ENSDART00000060302_1
ENSDART00000060302_2
ENSDART00000100665
GO:0003677
GO:0003684
GO:0005634
GO:0005694
GO:0006281
GO:0006289
GO:0009411
GO:0016567
GO:0043226
GO:0080008
GO:0090734
GT_Xhyb_NM_001083061.1_334865
GT_Xhyb_XM_005159034.1_334875
GT_Xhyb_XM_005159035.1_322945
JP004278
MADDr01006066
OTTDART00000016308
OTTDART00000016309
TC261760
Participates
as a component of
DDB1:PAR-DDB2 [nucleoplasm] (Danio rerio)
Other forms of this molecule
ddb2 [nucleoplasm]
Inferred From
PAR-DDB2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
L-glutamyl-5-poly(ADP-ribose) at unknown position
PsiMod Name
L-glutamyl-5-poly(ADP-ribose)
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Cross References
ENSEMBL
ENSDARP00000152759
,
ENSDART00000180316
,
ENSDARG00000041140
,
ENSDARG00000114723
,
ENSDART00000060302
,
ENSDARP00000060301
ZFIN
ZDB-GENE-050419-169
PRO
Q2YDS1
HMDB Protein
HMDBP12802
PDB
3EI3
,
4A0A
,
3EI1
,
4A08
,
4A0K
,
4A09
,
3EI2
,
4A0B
,
4A0L
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text