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dfna5 [cytosol]
Stable Identifier
R-DRE-9647689
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
GSDME(1-270), Q6J2R6
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
Toll-like Receptor Cascades (Danio rerio)
Regulation of TLR by endogenous ligand (Danio rerio)
HMGB1 release from cells (Danio rerio)
GSDME oligomer:PIP [plasma membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
Programmed Cell Death (Danio rerio)
Apoptosis (Danio rerio)
Intrinsic Pathway for Apoptosis (Danio rerio)
Apoptotic factor-mediated response (Danio rerio)
Release of apoptotic factors from the mitochondria (Danio rerio)
Release of Cytochrome c from mitochondria (Danio rerio)
GSDME:cardiolipin [mitochondrial outer membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
Regulated Necrosis (Danio rerio)
Pyroptosis (Danio rerio)
CASP3 cleaves GSDME (Danio rerio)
dfna5 [cytosol] (Danio rerio)
GSDME (1-270) binds PIPs (Danio rerio)
GSDME (1-270):PIPs [plasma membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
GSDME (1-270) binds cardiolipin (Danio rerio)
GSDME:cardiolipin [mitochondrial outer membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
GSDME oligomerizes (Danio rerio)
GSDME (1-270):PIPs [plasma membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
GSDME oligomer:PIP [plasma membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
HMGB1 release from cells (Danio rerio)
GSDME oligomer:PIP [plasma membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
Release of Cytochrome c from mitochondria (Danio rerio)
GSDME:cardiolipin [mitochondrial outer membrane] (Danio rerio)
dfna5 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6J2R6
Gene Names
dfna5
Reference Genes
BioGPS Gene:335722 dfna5
CTD Gene:335722 dfna5
ENSEMBL:ENSDARG00000040485
ENSEMBL:ENSDARG00000040485.6 dfna5
KEGG Gene (Danio rerio):335722 dfna5
Monarch:335722 dfna5
NCBI Gene:335722 dfna5
Reference Transcript
RefSeq:NM_001001947.1 dfna5
RefSeq:XM_021466634.1 dfna5
RefSeq:XM_005157961.4 dfna5
Other Identifiers
13031355
13277472
335722
A_15_P113290
A_15_P150501
CUST_5730_PI428451958
DRER07908
DRER37037
Dr.21797.1.S1_at
ENSDART00000059252
ENSDART00000059252_1
ENSDART00000059252_2
GO:0005737
GO:0005886
GO:0008219
GO:0009889
GO:0012501
GO:0016020
GO:0042471
GO:0042472
GO:0048856
GO:0070269
GT_Xhyb_NM_001001947.1_221765
GT_Xhyb_XM_005157962.1_147576
LOLS10847
MADDr01007601
NM_001001947
OTTDART00000026323
OTTDART00000026324
Participates
as an input of
GSDME oligomerizes (Danio rerio)
GSDME (1-270) binds PIPs (Danio rerio)
GSDME (1-270) binds cardiolipin (Danio rerio)
as a component of
GSDME (1-270):PIPs [plasma membrane] (Danio rerio)
GSDME:cardiolipin [mitochondrial outer membrane] (Danio rerio)
GSDME oligomer:PIP [plasma membrane] (Danio rerio)
as an output of
CASP3 cleaves GSDME (Danio rerio)
Other forms of this molecule
dfna5 [cytosol]
dfna5 [cytosol]
Inferred From
GSDME(1-270) [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005158018.1
,
XP_021322309.1
,
NP_001001947.1
ZFIN
ZDB-GENE-030131-7662
Ensembl
ENSDARG00000040485
,
ENSDART00000059252
,
ENSDARP00000146497
,
ENSDARP00000059251
,
ENSDART00000182869
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