Reactome | tmem186 [mitochondrial inner membrane]

tmem186 [mitochondrial inner membrane]

Stable Identifier

R-DRE-9708009

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

mitochondrial inner membrane

Synonyms

TMEM186, B3DI94

Locations in the PathwayBrowser

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Metabolism (Danio rerio)

- Aerobic respiration and respiratory electron transport (Danio rerio)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Danio rerio)
    - Respiratory electron transport (Danio rerio)
      - Complex I biogenesis (Danio rerio)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Danio rerio)
        
        550kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        370 kDa subcomplex [mitochondrial inner membrane] (Danio rerio)
        
        TMEM186:MT-ND3 [mitochondrial inner membrane] (Danio rerio)
        
        tmem186 [mitochondrial inner membrane] (Danio rerio)
        
        815kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        550kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        370 kDa subcomplex [mitochondrial inner membrane] (Danio rerio)
        
        TMEM186:MT-ND3 [mitochondrial inner membrane] (Danio rerio)
        
        tmem186 [mitochondrial inner membrane] (Danio rerio)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Danio rerio)
        
        Complex I [mitochondrial inner membrane] (Danio rerio)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Danio rerio)
        
        TMEM186:MT-ND3 [mitochondrial inner membrane] (Danio rerio)
        
        tmem186 [mitochondrial inner membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:B3DI94

Gene Names

tmem186

Reference Genes

BioGPS Gene:799142 tmem186

ENSEMBL:ENSDARG00000109974

KEGG Gene (Danio rerio):799142 tmem186

Monarch:799142 tmem186

NCBI Gene:799142 tmem186

Reference Transcript

RefSeq:NM_001135984.1 tmem186

Other Identifiers

13123476

799142

A_15_P442860

CUST_244_PI428451961

DRER19869

ENSDART00000112413

GT_Xhyb_NM_001135984.1_80151

GT_Xhyb_XM_005161767.1_427065

GT_Xhyb_XM_005161768.1_144366

Participates

as a component of

TMEM186:MT-ND3 [mitochondrial inner membrane] (Danio rerio)

Inferred From

TMEM186 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001129456.1

ZFIN

ZDB-GENE-081022-122

Ensembl

ENSDART00000182487, ENSDARP00000156317, ENSDARG00000109974

PRO

B3DI94

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