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NP [nucleoplasm]
Stable Identifier
R-FLU-188832
Type
Protein [EntityWithAccessionedSequence]
Species
Influenza A virus
Compartment
nucleoplasm
GO Cellular Component
host cell nucleoplasm
(0044095)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Export of Viral Ribonucleoproteins from Nucleus (Homo sapiens)
NEP/NS2 Interacts with the Cellular Export Machinery (Homo sapiens)
Binding of vRNP:M1:NEP complex to CRM1 export receptor (Homo sapiens)
vRNP Export Complex [nucleoplasm] (Homo sapiens)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP Export through the nuclear pore (Homo sapiens)
vRNP Export Complex [nucleoplasm] (Homo sapiens)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Viral RNP Complexes in the Host Cell Nucleus (Homo sapiens)
Binding of M1 to vRNP (Homo sapiens)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Binding of NEP/NS2 to vRNP:M1 (Homo sapiens)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP:M1:NEP [nucleoplasm] (Influenza A virus)
vRNP:M1 for Export [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Newly synthesized vRNP for export (Homo sapiens)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP destined for Export [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral Messenger RNA Synthesis (Homo sapiens)
Assembly of an Active Transcription Complex (Homo sapiens)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Elongation, Polyadenylation and Termination (Homo sapiens)
Initiated vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Priming and Initiation of Transcription (Homo sapiens)
Initiated vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA Transcription Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
cRNA Synthesis (Homo sapiens)
Initiation of cRNA Synthesis (Homo sapiens)
Initiated vRNA-cRNA Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
cRNA Extension (Homo sapiens)
Initiated vRNA-cRNA Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
cRNP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA Synthesis (Homo sapiens)
Initiation of vRNA Synthesis (Homo sapiens)
NP:PARP1 [nucleoplasm] (Homo sapiens)
NP [nucleoplasm] (Influenza A virus)
Initiated cRNA-vRNA Complex [nucleoplasm] (Influenza A virus)
cRNP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
cRNP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA Extension (Homo sapiens)
Initiated cRNA-vRNA Complex [nucleoplasm] (Influenza A virus)
cRNP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
cRNP [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
vRNP Assembly (Homo sapiens)
NP binds vRNA (Homo sapiens)
NP [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Docking and transport of the RNP:Karyopherin complex through the nuclear pore (Homo sapiens)
RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm] (Homo sapiens)
RNP Complex:Karyopherin alpha [nucleoplasm] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Release of the RNP into the host cell nucleus (Homo sapiens)
RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm] (Homo sapiens)
RNP Complex:Karyopherin alpha [nucleoplasm] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
NP [nucleoplasm] (Influenza A virus)
External Reference Information
External Reference
UniProt:P03466 NP
Gene Names
NP
Chain
chain:1-498
Reference Genes
BioGPS Gene:956531 NP
KEGG Gene (Hepatitis C Virus):956531 NP
Monarch:956531 NP
NCBI Gene:956531 NP
Reference Transcript
RefSeq:NC_002019.1 NP
Participates
as a component of
NP:PARP1 [nucleoplasm] (Homo sapiens)
cRNP [nucleoplasm] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [nucleoplasm] (Influenza A virus)
vRNA (Genomic):NP Complex [nucleoplasm] (Influenza A virus)
as an input of
vRNA Extension (Homo sapiens)
cRNA Extension (Homo sapiens)
NP binds vRNA (Homo sapiens)
This entity regulates
Positively
Initiation of cRNA Synthesis
(Homo sapiens)
Assembly of an Active Transcription Complex
(Homo sapiens)
Newly synthesized vRNP for export
(Homo sapiens)
Other forms of this molecule
NP [Golgi membrane]
NP [plasma membrane]
NP [extracellular region]
NP [endosome lumen]
NP [cytosol]
Cross References
RefSeq
NP_040982.1
PRO
P03466
PDB
4ZDU
,
2BST
,
4NQV
,
2WFS
,
5NQ3
,
5V5O
,
5NPZ
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03431 PB1
4
PB1 [extracellular region]
(R-FLU-169246)
PB1 [endosome lumen]
(R-FLU-189137)
PB1 [cytosol]
(R-FLU-195940)
PB1 [nucleoplasm]
(R-FLU-188843)
0.737
5
UniProt:P03428 PB2
5
PB2 [extracellular region]
(R-FLU-169238)
PB2 [endosome lumen]
(R-FLU-189140)
PB2 [cytosol]
(R-FLU-188851)
PB2 [cytosol]
(R-FLU-195946)
PB2 [nucleoplasm]
(R-FLU-188857)
0.586
3
UniProt:P03433 PA
4
PA [extracellular region]
(R-FLU-169243)
PA [endosome lumen]
(R-FLU-189131)
PA [cytosol]
(R-FLU-195948)
PA [nucleoplasm]
(R-FLU-188877)
0.586
3
UniProt:P03485 M
6
M1 [plasma membrane]
(R-FLU-195782)
M1 [extracellular region]
(R-FLU-169241)
M1 [endocytic vesicle membrane]
(R-FLU-189168)
M1 [endosome lumen]
(R-FLU-189155)
M1 [cytosol]
(R-FLU-169073)
M1 [nucleoplasm]
(R-FLU-186959)
0.573
2
UniProt:P03466 NP
6
NP [Golgi membrane]
(R-FLU-195740)
NP [plasma membrane]
(R-FLU-195752)
NP [extracellular region]
(R-FLU-169251)
NP [endosome lumen]
(R-FLU-189141)
NP [cytosol]
(R-FLU-188848)
NP [nucleoplasm]
(R-FLU-188832)
0.547
2
UniProt:O60684 KPNA6
2
KPNA6 [nucleoplasm]
(R-HSA-9734665)
KPNA6 [cytosol]
(R-HSA-9734672)
0.547
5
UniProt:Q8WV44 TRIM41
1
TRIM41 [cytosol]
(R-HSA-5688975)
0.499
5
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