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PB2 [cytosol]
Stable Identifier
R-FLU-195946
Type
Protein [EntityWithAccessionedSequence]
Species
Influenza A virus
Compartment
cytosol
GO Cellular Component
host cell cytosol
(0044164)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Export of Viral Ribonucleoproteins from Nucleus (Homo sapiens)
NEP/NS2 Interacts with the Cellular Export Machinery (Homo sapiens)
vRNP Export through the nuclear pore (Homo sapiens)
vRNP:M1:NEP:NP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Fusion and Uncoating of the Influenza Virion (Homo sapiens)
Uncoating of the Influenza Virion (Homo sapiens)
Ribonucleoprotein release from M1 proteins (Homo sapiens)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)
Docking and transport of the RNP:Karyopherin complex through the nuclear pore (Homo sapiens)
RNP:Karyopherin alpha:Karyopherin beta complex [cytosol] (Homo sapiens)
RNP Complex:Karyopherin alpha [cytosol] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein (Homo sapiens)
RNP Complex:Karyopherin alpha [cytosol] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Recruitment of Karyopherin Beta to form a Trimeric Complex (Homo sapiens)
RNP Complex:Karyopherin alpha [cytosol] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
RNP:Karyopherin alpha:Karyopherin beta complex [cytosol] (Homo sapiens)
RNP Complex:Karyopherin alpha [cytosol] (Homo sapiens)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Virus Assembly and Release (Homo sapiens)
Budding (Homo sapiens)
Membrane fusion (Homo sapiens)
Intracellular assembly complex [plasma membrane] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Packaging of Eight RNA Segments (Homo sapiens)
Association with M1 at cell membrane (Homo sapiens)
Intracellular assembly complex [plasma membrane] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
RNP pre-assembly complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
RNP association (Homo sapiens)
RNP pre-assembly complex [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 1 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 2 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 3 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 4 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 5 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 6 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 7 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
Segment 8 RNP [cytosol] (Influenza A virus)
PB2 [cytosol] (Influenza A virus)
External Reference Information
External Reference
UniProt:P03428 PB2
Gene Names
PB2
Chain
chain:1-759
Reference Genes
BioGPS Gene:956536 PB2
KEGG:vg:956536 PB2
Monarch:956536 PB2
NCBI Gene:956536 PB2
UCSC:P03428 PB2
Reference Transcript
RefSeq:NC_002023.1 PB2
Participates
as a component of
Segment 8 RNP [cytosol] (Influenza A virus)
Segment 5 RNP [cytosol] (Influenza A virus)
Segment 2 RNP [cytosol] (Influenza A virus)
Segment 1 RNP [cytosol] (Influenza A virus)
Segment 6 RNP [cytosol] (Influenza A virus)
Segment 4 RNP [cytosol] (Influenza A virus)
Segment 3 RNP [cytosol] (Influenza A virus)
Segment 7 RNP [cytosol] (Influenza A virus)
RNP pre-assembly complex [cytosol] (Influenza A virus)
Intracellular assembly complex [plasma membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [cytosol] (Influenza A virus)
vRNP:M1:NEP:NP [cytosol] (Influenza A virus)
as an input of
Association with M1 at cell membrane (Homo sapiens)
Other forms of this molecule
PB2 [extracellular region]
PB2 [endosome lumen]
PB2 [cytosol]
PB2 [nucleoplasm]
Cross References
ZINC - Substances
PB2_I34A1
ZINC target
P03428
PRO
P03428
ZINC - Predictions - Purchasable
PB2_I34A1
PDB
3WI1
,
3A1G
,
2ZTT
,
7JYX
,
7JYW
,
4ENF
,
4U6O
,
3CW4
,
3WI0
,
4J2R
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03431 PB1
4
PB1 [extracellular region]
(R-FLU-169246)
PB1 [endosome lumen]
(R-FLU-189137)
PB1 [cytosol]
(R-FLU-195940)
PB1 [nucleoplasm]
(R-FLU-188843)
0.632
3
UniProt:P03466 NP
6
NP [Golgi membrane]
(R-FLU-195740)
NP [plasma membrane]
(R-FLU-195752)
NP [extracellular region]
(R-FLU-169251)
NP [endosome lumen]
(R-FLU-189141)
NP [cytosol]
(R-FLU-188848)
NP [nucleoplasm]
(R-FLU-188832)
0.586
3
UniProt:Q12800 TFCP2
0.547
2
UniProt:P03433 PA
4
PA [extracellular region]
(R-FLU-169243)
PA [endosome lumen]
(R-FLU-189131)
PA [cytosol]
(R-FLU-195948)
PA [nucleoplasm]
(R-FLU-188877)
0.528
2
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