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RBX1 [nucleoplasm]
Stable Identifier
R-GGA-1234142
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
E1BSR9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
S Phase (Gallus gallus)
Synthesis of DNA (Gallus gallus)
Switching of origins to a post-replicative state (Gallus gallus)
Orc1 removal from chromatin (Gallus gallus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
KEAP1-NFE2L2 pathway (Gallus gallus)
Nuclear events mediated by NFE2L2 (Gallus gallus)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Gallus gallus)
BTRC binds p-S344, 347 NFE2L2 (Gallus gallus)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Gallus gallus)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub,pS335,S338,T NFE2L2 is degraded (Gallus gallus)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Regulation of BACH1 activity (Gallus gallus)
BACH1:FBXL17 binds SCF(SKP2) complex (Gallus gallus)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Gallus gallus)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Cellular response to hypoxia (Gallus gallus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Gallus gallus)
Nuclear VBC complex ubiquitinylates HIF-alpha (Gallus gallus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Gallus gallus)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
DNA Repair (Gallus gallus)
DNA Damage Bypass (Gallus gallus)
Recognition of DNA damage by PCNA-containing replication complex (Gallus gallus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Gallus gallus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Nucleotide Excision Repair (Gallus gallus)
Global Genome Nucleotide Excision Repair (GG-NER) (Gallus gallus)
DNA Damage Recognition in GG-NER (Gallus gallus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
PARP1 or PARP2 binds DDB2 at GG-NER site (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
UV-DDB ubiquitinates XPC (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Gallus gallus)
UV-DDB:COP9 Signalosome [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Dual Incision in GG-NER (Gallus gallus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Gallus gallus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Formation of Incision Complex in GG-NER (Gallus gallus)
CHD1L is recruited to GG-NER site (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Formation of the pre-incision complex in GG-NER (Gallus gallus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RNF111 ubiquitinates SUMOylated XPC (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Recruitment of XPA and release of CAK (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SUMOylation of XPC (Gallus gallus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TFIIH binds GG-NER site to form a verification complex (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Gallus gallus)
Dual incision in TC-NER (Gallus gallus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Gallus gallus)
TC-NER incision complex [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Gallus gallus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)
TC-NER pre-incision complex [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ERCC5 and RPA bind TC-NER site (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Formation of TC-NER Pre-Incision Complex (Gallus gallus)
ERCC8 (CSA) binds stalled RNA Pol II (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
UVSSA:USP7 deubiquitinates ERCC6 (Gallus gallus)
TC-NER pre-incision complex [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Gallus gallus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Gallus gallus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Gallus gallus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
DNA Replication (Gallus gallus)
Synthesis of DNA (Gallus gallus)
Switching of origins to a post-replicative state (Gallus gallus)
Orc1 removal from chromatin (Gallus gallus)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional regulation by RUNX2 (Gallus gallus)
Regulation of RUNX2 expression and activity (Gallus gallus)
SCF(SKP2) complex binds RUNX2 (Gallus gallus)
RUNX2:SCF(SKP2) [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SCF(SKP2) polyubiquitinates RUNX2 (Gallus gallus)
RUNX2:SCF(SKP2) [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Gallus gallus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Gallus gallus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Gallus gallus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Gallus gallus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Gallus gallus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Gallus gallus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Gallus gallus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'on' state (Gallus gallus)
GLI2,3 are degraded by the proteasome (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Gallus gallus)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Gallus gallus)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
RBX1 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BSR9
Reference Genes
ENSEMBL:ENSGALG00000011993
UCSC:E1BSR9
Participates
as a component of
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Gallus gallus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Gallus gallus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Gallus gallus)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Gallus gallus)
SPOP:CUL3:RBX1 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
UV-DDB [nucleoplasm] (Gallus gallus)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Gallus gallus)
SCF (SKP2) complex [nucleoplasm] (Gallus gallus)
Other forms of this molecule
RBX1 [cytosol]
Inferred From
RBX1 [nucleoplasm]
(Homo sapiens)
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