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C3b [extracellular region]
Stable Identifier
R-GGA-166832
Type
Complex
Species
Gallus gallus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Complement cascade (Gallus gallus)
Activation of C3 and C5 (Gallus gallus)
Activation of C5 (Gallus gallus)
C4b:C2a:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cleavage of C3 by C3 convertases (Gallus gallus)
C3 convertases [plasma membrane] (Gallus gallus)
C4b:C2a:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Formation of classic pathway C5 convertase (Gallus gallus)
C4b:C2a:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Initial triggering of complement (Gallus gallus)
Alternative complement activation (Gallus gallus)
C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
C3b binds to cell surface (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor B binds to surface-associated C3b (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b:CFB [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor D cleaves C3b-bound Factor B (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b:CFB [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Regulation of Complement cascade (Gallus gallus)
CD46 binds C3b (Gallus gallus)
CD46:Cell surface:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CD55 (DAF) binds C3bBb, C4bC2a (Gallus gallus)
C4bC2a, C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CD55:C3 convertase complexes [plasma membrane] (Gallus gallus)
CD55:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Gallus gallus)
CD55:C3 convertase complexes [plasma membrane] (Gallus gallus)
CD55:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CD55:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CFHR dimers bind C3b (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:C3b:CFHR dimers [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1 binds C3bBb/C4bC2a (Gallus gallus)
C4bC2a, C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Gallus gallus)
CR1:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Complement factor I binds to MCP, CR1:C4b, C3b (Gallus gallus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Gallus gallus)
CD46:Cell surface:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Gallus gallus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Gallus gallus)
CD46:Cell surface:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Complement factor I binds to extracellular Factor H:C3b (Gallus gallus)
CFH:C3b [extracellular region] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CFI:CFH:C3b [extracellular region] (Gallus gallus)
CFH:C3b [extracellular region] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Complement factor I binds to membrane-associated Factor H:C3b (Gallus gallus)
CFI:CFH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Displacement of C2a/Bb by CR1 (Gallus gallus)
CR1:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Gallus gallus)
CR1:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor H binds to C3b (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CFH:C3b [extracellular region] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor H binds to C3bBb (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:CFH, CFHR3:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor H binds to membrane-associated C3b (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor H displaces Bb (Gallus gallus)
Cell surface:CFH, CFHR3:C3bBb [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor I inactivates Factor H-boundC3b (Gallus gallus)
CFI:CFH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor I inactivates MCP/CR1-bound C4b/C3b (Gallus gallus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Gallus gallus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Gallus gallus)
CD46:Cell surface:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
CR1:C3b [plasma membrane] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
Factor I inactivates plasma Factor H-bound C3b (Gallus gallus)
CFI:CFH:C3b [extracellular region] (Gallus gallus)
CFH:C3b [extracellular region] (Gallus gallus)
C3b [extracellular region] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
C3 beta chain [extracellular region]
(Gallus gallus)
C3b alpha' [extracellular region]
(Gallus gallus)
Participates
as a component of
CD55:C3b [plasma membrane] (Gallus gallus)
CFH:C3b [extracellular region] (Gallus gallus)
CR1:C3b [plasma membrane] (Gallus gallus)
Cell surface:C3b:Bb [plasma membrane] (Gallus gallus)
Cell surface:C3b [plasma membrane] (Gallus gallus)
as an input of
Factor H binds to C3b (Gallus gallus)
C3b binds to cell surface (Gallus gallus)
as an output of
Cleavage of C3 by C3 convertases (Gallus gallus)
C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Gallus gallus)
Inferred From
C3b [extracellular region]
(Homo sapiens)
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