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AP-2 Complex [cytosol]
Stable Identifier
R-GGA-167712
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH-ephrin mediated repulsion of cells (Gallus gallus)
Clathrin internalises EPH:EFN complexes (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPHB:EFNB:F-actin:AP-2:Clathrrin:Dynamin [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by WNT (Gallus gallus)
Beta-catenin independent WNT signaling (Gallus gallus)
PCP/CE pathway (Gallus gallus)
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Gallus gallus)
FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Gallus gallus)
clathrin:AP-2 [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Clathrin-mediated endocytosis (Gallus gallus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Gallus gallus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Gallus gallus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
BAR domain proteins recruit dynamin (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Cargo recognition for clathrin-mediated endocytosis (Gallus gallus)
AP-2 directly binds some endocytic cargo (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
AP2:chlorpromazine [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
AP2 binds chlorpromazine (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
AP2:chlorpromazine [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Clathrin recruits PIK3C2A (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Clathrin recruits auxilins to the clathrin-coated vesicle (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
RAB5 and GAPVD1 bind AP-2 (Gallus gallus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
SNX9 recruits components of the actin polymerizing machinery (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 Complex [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
AP2A2(1-939) [cytosol]
(Gallus gallus)
AP2B1 [cytosol]
(Gallus gallus)
AP2M1 [cytosol]
(Gallus gallus)
AP2S1 [cytosol]
(Gallus gallus)
Participates
as a component of
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
Clathrin-coated vesicle [cytosol] (Gallus gallus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Gallus gallus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP2:chlorpromazine [cytosol] (Gallus gallus)
EPHB:EFNB:F-actin:AP-2:Clathrrin:Dynamin [plasma membrane] (Gallus gallus)
clathrin:AP-2 [plasma membrane] (Gallus gallus)
as an input of
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Gallus gallus)
AP-2 directly binds some endocytic cargo (Gallus gallus)
AP2 binds chlorpromazine (Gallus gallus)
Clathrin internalises EPH:EFN complexes (Gallus gallus)
Inferred From
AP-2 Complex [cytosol]
(Homo sapiens)
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