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TGFBR2 [plasma membrane]
Stable Identifier
R-GGA-170842
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
Q90999
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
CBL binds TGFBR2 (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2:CBL [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
CBL neddylates TGFBR2 (Gallus gallus)
TGFBR2:CBL [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
Dimeric TGF-beta-1 binds to the receptor (Gallus gallus)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
Downregulation of TGF-beta receptor signaling (Gallus gallus)
BAMBI interferes with the interaction of type I receptor with type II receptor (Gallus gallus)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
Degradation of TGF-beta receptor complex (Gallus gallus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Gallus gallus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Gallus gallus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Gallus gallus)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Gallus gallus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 phosphorylates TGFBR1 (Gallus gallus)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 recruits TGFBR1 (Gallus gallus)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Gallus gallus)
Disassembly of tight junctions (Gallus gallus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Gallus gallus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Gallus gallus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Gallus gallus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
TGFBR2 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q90999
Reference Genes
BioGPS Gene:396399
ENSEMBL:ENSGALG00000011442
ENSEMBL:ENSGALG00010002281.1
ENSEMBL:ENSGALG00015001149
KEGG Gene (Gallus gallus):396399
Monarch:396399
NCBI Gene:396399
Reference Transcript
RefSeq:NM_205428.1
Other Identifiers
396399
GO:0000166
GO:0001654
GO:0001666
GO:0001775
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004675
GO:0005024
GO:0005026
GO:0005515
GO:0005524
GO:0005539
GO:0005886
GO:0005901
GO:0006468
GO:0006915
GO:0007010
GO:0007178
GO:0007179
GO:0007507
GO:0009410
GO:0009653
GO:0009888
GO:0009897
GO:0010628
GO:0010718
GO:0010936
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0017002
GO:0023052
GO:0030154
GO:0030312
GO:0030324
GO:0030335
GO:0031012
GO:0032570
GO:0032924
GO:0034330
GO:0034713
GO:0034714
GO:0036211
GO:0038023
GO:0043235
GO:0045121
GO:0045216
GO:0046332
GO:0046872
GO:0048185
GO:0048568
GO:0048762
GO:0048856
GO:0048870
GO:0050431
GO:0050714
GO:0051496
GO:0060089
GO:0060317
GO:0060325
GO:0070483
GO:0070723
GO:0071363
GO:0140096
GO:1905075
GO:2000379
Gga.2645.1.S1_at
Participates
as an input of
CBL binds TGFBR2 (Gallus gallus)
Dimeric TGF-beta-1 binds to the receptor (Gallus gallus)
as a component of
TGFBR2:CBL [plasma membrane] (Gallus gallus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Gallus gallus)
TGFBR2 homodimer [plasma membrane] (Gallus gallus)
Other forms of this molecule
NEDD8-K556,K567-TGFBR2 [plasma membrane]
Inferred From
TGFBR2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_990759.1
Ensembl
ENSGALT00010005175
,
ENSGALP00010003047
,
ENSGALG00010002281
PRO
Q90999
PDB
1KS6
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