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Ghost homologue of SKP1 [cytosol]
Stable Identifier
R-GGA-174150
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
Mitotic G2-G2/M phases (Gallus gallus)
G2/M Transition (Gallus gallus)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Gallus gallus)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Gallus gallus)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SCF-FBXL7 ubiquitinates AURKA (Gallus gallus)
SCF-FBXL7:AURKA [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SCF:FBXL7 binds AURKA (Gallus gallus)
SCF-FBXL7:AURKA [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Regulation of mitotic cell cycle (Gallus gallus)
APC/C-mediated degradation of cell cycle proteins (Gallus gallus)
Regulation of APC/C activators between G1/S and early anaphase (Gallus gallus)
SCF-beta-TrCP mediated degradation of Emi1 (Gallus gallus)
Ubiquitination of Emi1 by SCF-beta-TrCP (Gallus gallus)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Gallus gallus)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Gallus gallus)
BTRC:CUL1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Gallus gallus)
BTRC:CUL1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Regulation of T cell activation by CD28 family (Gallus gallus)
Co-inhibition by PD-1 (Gallus gallus)
Regulation of PD-L1(CD274) expression (Gallus gallus)
Regulation of PD-L1(CD274) Post-translational modification (Gallus gallus)
GSK3B-mediated proteasomal degradation of PD-L1(CD274) (Gallus gallus)
Deubiquitination of CD274 (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
polyUb-p184,T189-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Ubiquitinated CD274 is degraded by the 26S proteasome (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
polyUb-p184,T189-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Ubiquitination of CD274 by BTRC-SCF E3-ligase complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
polyUb-p184,T189-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
p-S184,T180-CD274 binds to BTRC-SCF E3 ubiquitin ligase complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
p-S184,T180-CD274:BTRC E3 complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Prolactin receptor signaling (Gallus gallus)
PRLR binds SCF beta-TrCP complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Prolactin receptor is internalized (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Prolactin receptor ligands bind the prolactin receptor (Gallus gallus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-1 family signaling (Gallus gallus)
Interleukin-1 signaling (Gallus gallus)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'off' state (Gallus gallus)
Degradation of GLI1 by the proteasome (Gallus gallus)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
GLI3 is processed to GLI3R by the proteasome (Gallus gallus)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Signaling by WNT (Gallus gallus)
Degradation of beta-catenin by the destruction complex (Gallus gallus)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Degradation of ubiquitinated beta catenin by the proteasome (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
Ghost homologue of SKP1 [cytosol] (Gallus gallus)
Participates
as a component of
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
BTRC:CUL1:SKP1 [cytosol] (Gallus gallus)
Inferred From
SKP1 [cytosol]
(Homo sapiens)
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