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CD86 [plasma membrane]
Stable Identifier
R-GGA-179784
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
A0A3S5ZPT7
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent PI3K/Akt signaling (Gallus gallus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
CD28:PI3K [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
PI3K binds CD28 (Gallus gallus)
CD28:PI3K [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
CD28 dependent Vav1 pathway (Gallus gallus)
Activation of Cdc42 by pVav1 (Gallus gallus)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Gallus gallus)
CD28:Grb2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Activation of Rac1 by pVav1 (Gallus gallus)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Gallus gallus)
CD28:Grb2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Activation of Vav1 (Gallus gallus)
VAV1:PIP3:CD28:GRB2 [plasma membrane] (Gallus gallus)
CD28:Grb2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Gallus gallus)
CD28:Grb2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Grb2 binds CD28 (Gallus gallus)
CD28:Grb2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
CD28 homodimer binds B7-2 monomer (Gallus gallus)
CD28:B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Gads binds CD28 (Gallus gallus)
CD28:GRAP2 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Phosphorylation of CD28 (Gallus gallus)
CD28:B7-1,B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
CTLA4 inhibitory signaling (Gallus gallus)
CTLA-4 binds B7-1/B7-2 (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
PP2A:CTLA4:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
SHP2 phosphatase binds CTLA-4 (Gallus gallus)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
p-Y201,Y218-CTLA4 dimer:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Gallus gallus)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
p-Y201,Y218-CTLA4 dimer:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
CD28:PI3K [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
CD28:PI3K [plasma membrane] (Gallus gallus)
phospho CD28:B7-1/B7-2 [plasma membrane] (Gallus gallus)
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
CD86 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A3S5ZPT7
Reference Genes
ENSEMBL:ENSGALG00000014362
Participates
as an input of
CD28 homodimer binds B7-2 monomer (Gallus gallus)
as a component of
CD28:B7-2 [plasma membrane] (Gallus gallus)
as a member of
B7-1 homodimer/ B7-2 [plasma membrane] (Gallus gallus)
Inferred From
CD86 [plasma membrane]
(Homo sapiens)
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