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PDGF:Phospho-PDGF receptor dimer [plasma membrane]
Stable Identifier
R-GGA-186811
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PDGF (Gallus gallus)
Downstream signal transduction (Gallus gallus)
Activated PLC gamma dissociates from the PDGF receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
Activation of Src (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
Crk binds to the active PDGF receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
GRB2:SOS1 complex binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
Nck binds to the active PDGF receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PI3-kinase binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PLC-gamma binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
Phosphorylation of PLCgamma by PDGFR (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
SH2 domain of Src binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
SHP2 binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
STAT binds to the active receptor (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
p130Cas and C3G bind PDGFR bound Crk (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Active PDGF dimers (AA, AB, BB) [extracellular region]
(Gallus gallus)
Phospho- PDGF receptor dimer [plasma membrane]
(Gallus gallus)
Participates
as an input of
SH2 domain of Src binds to the active receptor (Gallus gallus)
STAT binds to the active receptor (Gallus gallus)
Nck binds to the active PDGF receptor (Gallus gallus)
SHP2 binds to the active receptor (Gallus gallus)
Crk binds to the active PDGF receptor (Gallus gallus)
PI3-kinase binds to the active receptor (Gallus gallus)
PLC-gamma binds to the active receptor (Gallus gallus)
GRB2:SOS1 complex binds to the active receptor (Gallus gallus)
as a component of
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Gallus gallus)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Gallus gallus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Gallus gallus)
as an output of
Activated PLC gamma dissociates from the PDGF receptor (Gallus gallus)
Inferred From
PDGF:Phospho-PDGF receptor dimer [plasma membrane]
(Homo sapiens)
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