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CCNA:p-T160-CDK2 [nucleoplasm]
Stable Identifier
R-GGA-187952
Type
Complex
Species
Gallus gallus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
Mitotic G1 phase and G1/S transition (Gallus gallus)
G1/S Transition (Gallus gallus)
Cyclin E associated events during G1/S transition (Gallus gallus)
SCF(Skp2)-mediated degradation of p27/p21 (Gallus gallus)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Gallus gallus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Ubiquitination of phospho-p27/p21 (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Mitotic G2-G2/M phases (Gallus gallus)
G2 Phase (Gallus gallus)
Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Gallus gallus)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
G2/M Transition (Gallus gallus)
Cyclin A/B1/B2 associated events during G2/M transition (Gallus gallus)
CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Gallus gallus)
CCNA:p-CDK1/2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Regulation of mitotic cell cycle (Gallus gallus)
APC/C-mediated degradation of cell cycle proteins (Gallus gallus)
Regulation of APC/C activators between G1/S and early anaphase (Gallus gallus)
Association of Cyclin A:Cdk2 with Cdh1 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Gallus gallus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
S Phase (Gallus gallus)
Cyclin A:Cdk2-associated events at S phase entry (Gallus gallus)
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
SCF(Skp2)-mediated degradation of p27/p21 (Gallus gallus)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Gallus gallus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Ubiquitination of phospho-p27/p21 (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Gallus gallus)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Gallus gallus)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Synthesis of DNA (Gallus gallus)
Switching of origins to a post-replicative state (Gallus gallus)
CDK-mediated phosphorylation and removal of Cdc6 (Gallus gallus)
Cdc6 protein is phosphorylated by CDK (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Orc1 removal from chromatin (Gallus gallus)
Orc1 is phosphorylated by cyclin A/CDK2 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular Senescence (Gallus gallus)
Senescence-Associated Secretory Phenotype (SASP) (Gallus gallus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Gallus gallus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
DNA Repair (Gallus gallus)
DNA Double-Strand Break Repair (Gallus gallus)
Homology Directed Repair (Gallus gallus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Gallus gallus)
Processing of DNA double-strand break ends (Gallus gallus)
CDK2 phosphorylates RBBP8 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
MRN complex binds CDK2 and RBBP8 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
DNA Replication (Gallus gallus)
Synthesis of DNA (Gallus gallus)
Switching of origins to a post-replicative state (Gallus gallus)
CDK-mediated phosphorylation and removal of Cdc6 (Gallus gallus)
Cdc6 protein is phosphorylated by CDK (Gallus gallus)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Orc1 removal from chromatin (Gallus gallus)
Orc1 is phosphorylated by cyclin A/CDK2 (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
Regulation of TP53 Activity (Gallus gallus)
Regulation of TP53 Expression and Degradation (Gallus gallus)
Regulation of TP53 Degradation (Gallus gallus)
(CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Gallus gallus)
CCNA:p-CDK1/2 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CCNA [nucleoplasm]
(Gallus gallus)
phospho-p-T160-CDK2 [nucleoplasm]
(Gallus gallus)
Participates
as an input of
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Gallus gallus)
Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Gallus gallus)
Association of Cyclin A:Cdk2 with Cdh1 (Gallus gallus)
MRN complex binds CDK2 and RBBP8 (Gallus gallus)
as a component of
CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] (Gallus gallus)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Gallus gallus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Gallus gallus)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Gallus gallus)
as an output of
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Gallus gallus)
CDK2 phosphorylates RBBP8 (Gallus gallus)
as a member of
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Gallus gallus)
CCNA:p-CDK1/2 [nucleoplasm] (Gallus gallus)
Inferred From
CCNA:p-T160-CDK2 [nucleoplasm]
(Homo sapiens)
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