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AXIN1 [cytosol]
Stable Identifier
R-GGA-195249
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
AXIN1, A0A1D5P395
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by WNT (Gallus gallus)
Degradation of beta-catenin by the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Degradation of AXIN (Gallus gallus)
AXIN is ubiquitinated by SMURF2 (Gallus gallus)
AXIN:SMURF2 [cytosol] (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
SMURF2 binds AXIN (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
AXIN:SMURF2 [cytosol] (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
Tankyrase ADP-ribosylates AXIN (Gallus gallus)
AXIN:TNKS [cytosol] (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
Tankyrase binds AXIN (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
AXIN:TNKS [cytosol] (Gallus gallus)
AXIN [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Gallus gallus)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Gallus gallus)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5P395
Gene Names
AXIN1
Reference Genes
BioGPS Gene:395786 AXIN1
ENSEMBL:ENSGALG00000029402
ENSEMBL:ENSGALG00010016911.1 AXIN1
Monarch:395786 AXIN1
NCBI Gene:395786 AXIN1
Reference Transcript
RefSeq:XM_015294136.1 AXIN1
Other Identifiers
395786
GO:0000209
GO:0001932
GO:0001934
GO:0002039
GO:0005634
GO:0005730
GO:0005737
GO:0005856
GO:0005886
GO:0005938
GO:0006351
GO:0006355
GO:0006913
GO:0007010
GO:0007605
GO:0008013
GO:0009950
GO:0009953
GO:0010629
GO:0010800
GO:0015630
GO:0016055
GO:0016328
GO:0019899
GO:0019901
GO:0019904
GO:0023052
GO:0030154
GO:0030163
GO:0030178
GO:0030511
GO:0030877
GO:0031122
GO:0031398
GO:0031410
GO:0031625
GO:0032436
GO:0032991
GO:0033138
GO:0034244
GO:0036211
GO:0036342
GO:0042802
GO:0042803
GO:0043226
GO:0043621
GO:0044725
GO:0045599
GO:0045732
GO:0046330
GO:0046332
GO:0048318
GO:0048320
GO:0048468
GO:0048471
GO:0048856
GO:0050877
GO:0051248
GO:0060070
GO:0060090
GO:0060322
GO:0060828
GO:0065003
GO:0070411
GO:0070412
GO:0071944
GO:0090090
GO:1990756
GO:1990909
GO:2000060
GT_A_87_P071976
GT_A_87_P247593
Gga.464.1.S1_at
Gga.464.2.S1_a_at
Gga.464.2.S1_s_at
GgaAffx.20094.1.S1_s_at
Participates
as a member of
AXIN [cytosol] (Gallus gallus)
as a component of
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
Other forms of this molecule
AXIN1 [cytosol]
phospho-AXIN1 [cytosol]
phospho-AXIN1 [cytosol]
phospho-AXIN1 [cytosol]
Inferred From
AXIN1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015149622.1
OpenTargets
ENSG00000103126
Ensembl
ENSGALP00010023787
,
ENSGALG00010016911
,
ENSGALT00010040823
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