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NCK1 [cytosol]
Stable Identifier
R-GGA-204885
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
NCK2, F1P4Q4
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Gallus gallus)
Nephrin family interactions (Gallus gallus)
Nephrin mediated activation of N-WASP (Gallus gallus)
NEPH1:p-Nephrin:Fyn:NCK [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
NEPH1:p-Nephrin:Fyn:NCK:N-WASP [plasma membrane] (Gallus gallus)
NEPH1:p-Nephrin:Fyn:NCK [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
Ephrin signaling (Gallus gallus)
EFNB:GRB4 binds GIT1 (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
GIT1 binds bPIX (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PAK binds RAC and bPIX (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PAKs autophosphorylate (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PAKs phosphorylate MLC (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
bPIX exchanges GTP for GDP on RAC, activating it (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
p-EFNB binds GRB4 (Gallus gallus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PDGF (Gallus gallus)
Downstream signal transduction (Gallus gallus)
Nck binds to the active PDGF receptor (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
CDC42:GTP binds PAK2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
FYN autophosphorylates (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
FYN phosphorylates PAK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PAK2 autophorylates (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
PAK2 binds NCK (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
p-6Y-VEGFR2 binds FYN (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
p-6Y-VEGFR2 binds NCK (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
p38 MAPK activation by VEGFR (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RHOU GTPase cycle (Gallus gallus)
RHOU binds effectors at the plasma membrane (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
RHOU:GTP:RHOU effectors [plasma membrane] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
RHOV GTPase cycle (Gallus gallus)
RHOV binds effectors at the plasma membrane (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
RHOV:GTP:RHOV effectors [plasma membrane] (Gallus gallus)
RHOV effectors [cytosol] (Gallus gallus)
NCK1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1P4Q4
Gene Names
NCK1
Reference Genes
ENSEMBL:ENSGALG00000016799
ENSEMBL:ENSGALG00010012944.1 NCK1
Other Identifiers
418727
GO:0001784
GO:0002376
GO:0005515
GO:0005737
GO:0005783
GO:0005829
GO:0006351
GO:0006355
GO:0006417
GO:0007010
GO:0007015
GO:0007155
GO:0007165
GO:0012501
GO:0012506
GO:0016477
GO:0023052
GO:0030032
GO:0030838
GO:0030971
GO:0033137
GO:0035591
GO:0036211
GO:0036493
GO:0042102
GO:0043226
GO:0044877
GO:0045944
GO:0048013
GO:0048870
GO:0060090
GO:0065003
GO:0097110
GO:1902237
GO:1903898
GO:1903912
GO:1990441
GT_A_87_P036542
Gga.9033.1.S1_at
GgaAffx.12339.1.S1_s_at
Participates
as a candidate of
RHOV effectors [cytosol] (Gallus gallus)
as a member of
RHOU effectors [cytosol] (Gallus gallus)
as an input of
p-EFNB binds GRB4 (Gallus gallus)
Nck binds to the active PDGF receptor (Gallus gallus)
p-6Y-VEGFR2 binds NCK (Gallus gallus)
as a component of
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Gallus gallus)
NEPH1:p-Nephrin:Fyn:NCK [plasma membrane] (Gallus gallus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
Inferred From
NCK1,NCK2 [cytosol]
(Homo sapiens)
NCK2 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000158092
Ensembl
ENSGALG00010012944
,
ENSGALT00010031073
,
ENSGALP00010018068
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