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Integrin alphaVbeta3 [plasma membrane]
Stable Identifier
R-GGA-210216
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to mechanical stimuli (Gallus gallus)
Response of endothelial cells to shear stress (Gallus gallus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Gallus gallus)
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Extracellular matrix organization (Gallus gallus)
ECM proteoglycans (Gallus gallus)
TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Gallus gallus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
TNC:Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Gallus gallus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VTN:Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Elastic fibre formation (Gallus gallus)
Fibrillin-1 binds integrins (Gallus gallus)
Fibrilin-1:Fibrilin-binding integrins [plasma membrane] (Gallus gallus)
Fibrilin-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Fibrilin-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Molecules associated with elastic fibres (Gallus gallus)
Latent TGF-beta-1 binds integrins (Gallus gallus)
LAP1 binding-integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Gallus gallus)
LAP1 binding-integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Latent TGF-beta-3 binds integrins (Gallus gallus)
LAP3-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Gallus gallus)
LAP3-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin cell surface interactions (Gallus gallus)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Gallus gallus)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Gallus gallus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Gallus gallus)
Canstatin:Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Gallus gallus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Gallus gallus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Interaction of integrin alphaVbeta3 with Fibrillin (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Interaction of integrin alphaVbeta3 with PECAM1 (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Interaction of integrin alphaVbeta3 with Tenascin (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Tetrastatin binds integrin alphaVbeta3 (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Gallus gallus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Non-integrin membrane-ECM interactions (Gallus gallus)
Syndecan interactions (Gallus gallus)
Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Gallus gallus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Syndecan-1:Integrin alpha2beta1 (alpha6beta4) [plasma membrane] (Gallus gallus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
PECAM1 interactions (Gallus gallus)
Interaction of integrin alphaVbeta3 with PECAM1 (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
PTK2beta binds alphaVbeta3 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
SRC-1 phosphorylates PTK2-beta (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Latent TGF-beta-1 binds integrins (Gallus gallus)
LAP1 binding-integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Gallus gallus)
LAP1 binding-integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Latent TGF-beta-3 binds integrins (Gallus gallus)
LAP3-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Gallus gallus)
LAP3-binding integrins [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ITGAV(31-1048) [plasma membrane]
(Gallus gallus)
ITGB3 [plasma membrane]
(Gallus gallus)
Participates
as a member of
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Gallus gallus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Gallus gallus)
Fibrilin-binding integrins [plasma membrane] (Gallus gallus)
Integrins [plasma membrane] (Gallus gallus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Gallus gallus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Gallus gallus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Gallus gallus)
LAP1 binding-integrins [plasma membrane] (Gallus gallus)
LAP3-binding integrins [plasma membrane] (Gallus gallus)
as an input of
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Gallus gallus)
Interaction of integrin alphaVbeta3 with Tenascin (Gallus gallus)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Gallus gallus)
Interaction of integrin alphaVbeta3 with Fibrillin (Gallus gallus)
Tetrastatin binds integrin alphaVbeta3 (Gallus gallus)
Interaction of integrin alphaVbeta3 with PECAM1 (Gallus gallus)
as a component of
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Gallus gallus)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Gallus gallus)
This entity regulates
Positively
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow
(Gallus gallus)
Inferred From
Integrin alphaVbeta3 [plasma membrane]
(Homo sapiens)
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