Chicken complement factor C3 has been isolated, mapped and characterized [Laursen I and Koch C 1989; Mavrodis M et al 1995]. Chicken C3 consists of 1652 amino acids and shares 54% identity with its human and mouse counterparts. Like its mammalian orthologs chicken C3 has a two-chain structure with an alpha chain (11kDa) and a beta-chain (70kDa). Upon complement activation chicken C3 is cleaved into fragments that resemble mammalian C3a and C3b [Laursen I and Koch C 1989].
Laursen, I, Koch, C
Mavroidis, M, Lambris, JD, Sunyer, JO
serine-type endopeptidase activity of C3i:factor Bb [extracellular region]
© 2024 Reactome