Reactome | phospho-IRS4 [plasma membrane]

phospho-IRS4 [plasma membrane]

Stable Identifier

R-GGA-2424302

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

p-Y-IRS4, A0A8V0YL35

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Gallus gallus)
    - IGF1R signaling cascade (Gallus gallus)
      - IRS-related events triggered by IGF1R (Gallus gallus)
        
        IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Gallus gallus)
        
        IGF1,2:p-IGF1R:p-IRS1,2,4 [plasma membrane] (Gallus gallus)
        
        p-IRS1,2,4 [plasma membrane] (Gallus gallus)
        
        phospho-IRS4 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0YL35

Gene Names

IRS4

Reference Genes

BioGPS Gene:422347 IRS4

ENSEMBL:ENSGALG00010015557.1

Monarch:422347 IRS4

NCBI Gene:422347 IRS4

UCSC:A0A8V0YL35 IRS4

Reference Transcript

Other Identifiers

422347

GO:0005158

GO:0005829

GO:0005886

GO:0007165

GO:0008286

GO:0043548

GT_A_87_P018349

Gga.13569.1.S1_at

GgaAffx.5086.1.S1_at

Participates

as a member of

p-IRS1,2,4 [plasma membrane] (Gallus gallus)

Other forms of this molecule

IRS4 [plasma membrane]

Inferred From

p-Y-IRS4 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_003641132.4, XP_040526526.1

ENSEMBL

ENSGALT00010037390, ENSGALP00010021661, ENSGALG00010015557

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